- Erianin
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- $41.00 / 5mg
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2026-04-14
- CAS:95041-90-0
- Min. Order:
- Purity: 99.48%
- Supply Ability: 10g
- Erianin
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- $0.10 / 1KG
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2025-12-24
- CAS:95041-90-0
- Min. Order: 1KG
- Purity: 98.0%
- Supply Ability: 10
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| | PHENOL, 2-METHOXY-5-[2-(3,4,5-TRIMETHOXYPHENYL)ETHYL]- Basic information |
| Product Name: | PHENOL, 2-METHOXY-5-[2-(3,4,5-TRIMETHOXYPHENYL)ETHYL]- | | Synonyms: | 3'-Hydroxy-3,4,4',5-tetraMethoxybibenzyl;PHENOL, 2-METHOXY-5-[2-(3,4,5-TRIMETHOXYPHENYL)ETHYL]-;Erianin 95041-90-0;Inhibitor,Erianin,inhibit,Bacterial;Erianin-RM;Erianin, 10 mM in DMSO | | CAS: | 95041-90-0 | | MF: | C18H22O5 | | MW: | 318.36 | | EINECS: | 1312995-182-4 | | Product Categories: | | | Mol File: | 95041-90-0.mol | ![PHENOL, 2-METHOXY-5-[2-(3,4,5-TRIMETHOXYPHENYL)ETHYL]- Structure](CAS/GIF/95041-90-0.gif) |
| | PHENOL, 2-METHOXY-5-[2-(3,4,5-TRIMETHOXYPHENYL)ETHYL]- Chemical Properties |
| Boiling point | 439.1±40.0 °C(Predicted) | | density | 1.147 | | storage temp. | 2-8°C | | solubility | DMSO:PBS (pH 7.2) (1:8):0.11(Max Conc. mg/mL);0.35(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);94.23(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);15.71(Max Conc. mM) | | form | A crystalline solid | | pka | 9.99±0.10(Predicted) | | color | White to off-white | | Major Application | food and beverages | | InChI | InChI=1S/C18H22O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h7-11,19H,5-6H2,1-4H3 | | InChIKey | UXDFUVFNIAJEGM-UHFFFAOYSA-N | | SMILES | C1(O)=CC(CCC2=CC(OC)=C(OC)C(OC)=C2)=CC=C1OC |
| WGK Germany | WGK 3 | | HS Code | 29089990 | | Storage Class | 11 - Combustible Solids |
| | PHENOL, 2-METHOXY-5-[2-(3,4,5-TRIMETHOXYPHENYL)ETHYL]- Usage And Synthesis |
| Chemical Properties | White or off-white powder | | Uses | Erianin acts as a promising anticancer agent. Cytotoxic compound strongly inhibits tubulin polymerization in cell mitosis. | | Synthesis | General procedure for the synthesis of 2-methoxy-5-(3,4,5-trimethoxyphenethyl)phenol (SIT-1) from the compound (CAS:117048-62-1): compound CA-4 (1.0 g, 3.16 mmol) and 10% palladium-carbon catalyst (0.1 g) were dissolved in methanol (20 mL) and the reaction was stirred for 2 h at room temperature under hydrogen atmosphere. . Upon completion of the reaction, the palladium-carbon catalyst was removed by filtration and the filtrate was dried with anhydrous sodium sulfate and concentrated to afford the target product SIT-1 in 91% yield. The product was characterized by 1H NMR (500 MHz, CDCl3): δ 6.81 (d, 1H, J=3.0 Hz), 6.77 (d, 1H, J=8.0 Hz), 6.64-6.66 (m, 1H), 6.38 (s, 2H), 5.61 (s, 1H), 3.87 (s, 3H), 3.83 (s, 9H), 2.82 (s 4H). | | References | [1] Journal of Medicinal Chemistry, 1995, vol. 38, # 10, p. 1666 - 1672
[2] Chinese Chemical Letters, 2015, vol. 26, # 8, p. 993 - 999
[3] Journal of Chemical Research, 2008, # 6, p. 354 - 356
[4] ChemMedChem, 2011, vol. 6, # 3, p. 488 - 497 |
| | PHENOL, 2-METHOXY-5-[2-(3,4,5-TRIMETHOXYPHENYL)ETHYL]- Preparation Products And Raw materials |
| Raw materials | Phenol, 2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethynyl]--->TRIPHENYL-(3,4,5-TRIMETHOXY-BENZYL)-PHOSPHONIUM, BROMIDE-->3-tert-Butyldimethylsiloxy-4-methoxybenzaldehyde-->3,4,5-Trimethoxybenzyl alcohol-->Phenol, 2-methoxy-5-[(1E)-2-(3,4,5-trimethoxyphenyl)ethenyl]--->3,4,5-Trimethoxybenzaldehyde-->Methanol-->Hydrogen-->Palladium-->Activated carbon |
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