Eosin 5-isothiocyanate

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Eosin 5-isothiocyanate Basic information
Product Name:Eosin 5-isothiocyanate
Synonyms:eosine-5-isothiocyanate;EITC;EOSIN 5-ISOTHIOCYANATE FOR FLUOR- &;EOSIN-5-ISOTHIOCYANATE, FOR FLUOR-ESCENC E;Spiroisobenzofuran-1(3H),9-9Hxanthen-3-one, 2,4,5,7-tetrabromo-3,6-dihydroxy-5-isothiocyanato-;Eosin 5-isothiocyanate-Celite(R);Eosin-5-isothiocyanate [2',4',5',7'-TetrabroMofluorescein-5-isothiocyanate];Eosin 5-isothiocyanate–Celite?
CAS:60520-47-0
MF:C21H7Br4NO5S
MW:704.97
EINECS:
Product Categories:
Mol File:60520-47-0.mol
Eosin 5-isothiocyanate Structure
Eosin 5-isothiocyanate Chemical Properties
Boiling point 719.1±60.0 °C(Predicted)
density 2.33±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka6.93±0.20(Predicted)
form Solid
color Red to Dark Red
Stability:Light sensitive
InChI1S/C21H7Br4NO5S/c22-12-4-10-14(8-2-1-7(26-6-32)3-9(8)21(29)30)11-5-13(23)18(28)16(25)20(11)31-19(10)15(24)17(12)27/h1-5,27H,(H,29,30)
InChIKeyMCXYFYWNOWPDMA-UHFFFAOYSA-N
SMILESOC(=O)c1cc(ccc1C2=C3C=C(Br)C(=O)C(Br)=C3Oc4c(Br)c(O)c(Br)cc24)N=C=S
Safety Information
Hazard Codes Xn
Risk Statements 42
Safety Statements 22-24/25
WGK Germany 3
8-9
Storage Class13 - Non Combustible Solids
Hazard ClassificationsResp. Sens. 1
Skin Sens. 1
MSDS Information
ProviderLanguage
SigmaAldrich English
Eosin 5-isothiocyanate Usage And Synthesis
Description

Eosine-5-isothiocyanate is an amine-reactive fluorescent probe for protein rotational diffusion measurement.

UsesEosin 5-isothiocyanate (EITC) is a fluorescence probe. EITC tagged molecules may be used together with fluorescein-5′-isothiocyanate (FITC) tagged molecules in fluoresce resonance energy transfer (FRET) based assays.
UsesAcceptor fluorophore. Measurement of rotational diffusion of proteins; In fluorescence energy transfer studies: R. Wagner et al.; FEBS Lett. 230, 109 (1988)
DefinitionChEBI: The 2',4',5',7'-tetrabromo-5-isothiocyanato derivative of fluorescein; exhibits phosphorescence with an emission maximum at ~680 nm.
Eosin 5-isothiocyanate Preparation Products And Raw materials
Tag:Eosin 5-isothiocyanate(60520-47-0) Related Product Information
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