- ML402
-
- $44.00
-
2026-08-08
- CAS:298684-44-3
- Purity: 99.71%
- Supply Ability: 10g
- ML402
-
-
2026-08-07
- CAS:298684-44-3
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1000kg
|
| Product Name: | ML402 | | Synonyms: | ML402;ML402;ML-402 ;ML 402;2-Thiophenecarboxamide, N-[2-(4-chloro-2-methylphenoxy)ethyl]-;ML402 (TREK-1/2 Activator);ML402, 10 mM in DMSO | | CAS: | 298684-44-3 | | MF: | C14H14ClNO2S | | MW: | 295.78 | | EINECS: | | | Product Categories: | | | Mol File: | 298684-44-3.mol |  |
| | ML402 Chemical Properties |
| Boiling point | 508.4±45.0 °C(Predicted) | | density | 1.272±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 150 mg/mL (507.13 mM) | | pka | 13.84±0.46(Predicted) | | form | Solid | | color | White to off-white | | InChI | 1S/C14H14ClNO2S/c1-10-9-11(15)4-5-12(10)18-7-6-16-14(17)13-3-2-8-19-13/h2-5,8-9H,6-7H2,1H3,(H,16,17) | | InChIKey | RULQUKFOBAPKKR-UHFFFAOYSA-N | | SMILES | ClC1=CC=C(OCCNC(C2=CC=CS2)=O)C(C)=C1 |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | ML402 Usage And Synthesis |
| Description | ML402 is a selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) activator. | | Uses | ML402, a thiophene-carboxamide, is a selective K2P2.1(TREK-1) and K2P10.1(TREK-2) activator. ML402 is inactive against K2P4.1(TRAAK)[1]. | | storage | Store at +4°C | | References | [1] Lolicato M, et al. K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site. Nature. 2017 Jul 20;547(7663):364-368. DOI:10.1038/nature22988 |
| | ML402 Preparation Products And Raw materials |
|