t-boc-N-amido-PEG5-azide manufacturers
- Azido-PEG5-NHBoc
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- $0.00 / 1g
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2025-06-07
- CAS:911209-07-9
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | t-boc-N-amido-PEG5-azide Basic information |
| Product Name: | t-boc-N-amido-PEG5-azide | | Synonyms: | t-boc-N-amido-PEG5-Azido;BocNH-PEG5-CH2CH2N3;tert-Butyl (17-azido-3,6,9,12,15-pentaoxaheptadecyl)carbamate;Azido-PEG5-NHBoc;Boc-NH-PEG5-azide;Azido-PEG5-Boc Amine;BocNH-PEG5-CH2CH2N3/5,8,11,14,17-Pentaoxa-2-azanonadecanoic acid, 19-azido-, 1,1-dimethylethyl ester | | CAS: | 911209-07-9 | | MF: | C17H34N4O7 | | MW: | 406.47446 | | EINECS: | | | Product Categories: | | | Mol File: | 911209-07-9.mol |  |
| | t-boc-N-amido-PEG5-azide Chemical Properties |
| storage temp. | Store at Room Tem. | | solubility | Soluble in Water, DMSO, DCM, DMF |
| | t-boc-N-amido-PEG5-azide Usage And Synthesis |
| Description | t-boc-N-amido-PEG5-azide is N-Boc protected crosslinker. The hydrophilic PEG spacer increases solubility in aqueous media. the compound can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine. | | Uses | Boc-NH-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-NH-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | t-boc-N-amido-PEG5-azide Preparation Products And Raw materials |
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