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5-Chloropyrimidin-2-amine

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Company Name: Hebei Chuanghai Biotechnology Co., Ltd
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Products Intro: Product Name:5-Chloropyrimidin-2-amine
CAS:5428-89-7
Purity:99% Package:1KG;10.00;USD
Company Name: Zibo Shiji Zhonglian Medical Technology Co., Ltd.
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Products Intro: Product Name:5-Chloropyrimidin-2-amine
CAS:5428-89-7
Purity:99.0% Package:1000KG;1USD
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Products Intro: Product Name:2-Amino-5-chloropyrimidine
CAS:5428-89-7
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
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Products Intro: Product Name:5-Chloropyrimidin-2-amine
CAS:5428-89-7
Purity:98% Package:1KG;1USD
Company Name: Alchem Pharmtech,Inc.
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Products Intro: Product Name:2-Amino-5-chloropyrimidine
CAS:5428-89-7
Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-00937

5-Chloropyrimidin-2-amine manufacturers
5-Chloropyrimidin-2-amine Basic information
Product Name:5-Chloropyrimidin-2-amine
Synonyms:TIMTEC-BB SBB005486;5-CHLORO-2-PYRIMIDINAMINE;2-AMINO-5-CHLOROPYRIMIDINE;5-chloropyrimidin-2-amine;2-Pyrimidinamine, 5-chloro- (9CI);5-chlorpyrimidin-2-amin;5-chloro-2-pyrimidinylamine;5-Chloropyrimidin-2-amine, 2-Amino-5-chloro-1,3-diazine
CAS:5428-89-7
MF:C4H4ClN3
MW:129.55
EINECS:226-581-2
Product Categories:Heterocycle-Pyrimidine series;Heterocyclic Building Blocks;Pyrimidines;PyrimidinesHeterocyclic Building Blocks;PYRIMIDINE;Pyridines, Pyrimidines, Purines and Pteredines;Biochemistry;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Building Blocks;Halogenated Heterocycles
Mol File:5428-89-7.mol
5-Chloropyrimidin-2-amine Structure
5-Chloropyrimidin-2-amine Chemical Properties
Melting point 235-238 °C (lit.)
Boiling point 314.6±34.0 °C(Predicted)
density 1.437±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka1.93±0.10(Predicted)
form powder to crystal
color White to Almost white
BRN 110914
InChI1S/C4H4ClN3/c5-3-1-7-4(6)8-2-3/h1-2H,(H2,6,7,8)
InChIKeyOQZMDDKDHRIGDY-UHFFFAOYSA-N
SMILESNc1ncc(Cl)cn1
CAS DataBase Reference5428-89-7(CAS DataBase Reference)
NIST Chemistry Reference2-Amino-5-chloropyrimidine(5428-89-7)
EPA Substance Registry System2-Pyrimidinamine, 5-chloro- (5428-89-7)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-41
Safety Statements 26-36/37
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS UV6329500
Hazard Note Irritant
TSCA TSCA listed
HazardClass 6.1
PackingGroup Ⅲ
HS Code 29335990
Storage Class6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard ClassificationsAcute Tox. 3 Oral
Eye Dam. 1
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
5-Chloropyrimidin-2-amine Usage And Synthesis
Uses5-Chloropyrimidin-2-amine is an useful reagent of research interest in the preparation of JAK2 inhibitors for the treatment of myeloproliferative disorders and SIRT2 inhibitors for the treatment of Huntington''s disease.
Synthesis Reference(s)Journal of the American Chemical Society, 64, p. 567, 1942 DOI: 10.1021/ja01255a030
5-Chloropyrimidin-2-amine Preparation Products And Raw materials
Raw materials2-CHLOROMALONALDEHYDE-->Mucochloric acid-->Guanidine nitrate-->Guanidine carbonate
Preparation Products2-Aminopyrimidine-->N-(5-Chloropyrimidin-2-yl)acetamide
Tag:5-Chloropyrimidin-2-amine(5428-89-7) Related Product Information
Glucosamine 2-Aminopyrimidine 3-Aminophenol 6-Aminocaproic acid EC 2.6.1.2 Bis(2-ethylhexyl)amine Dibenzylamine Triallylamine Acetaminophen Tris(hydroxymethyl)aminomethane Glycine Aminoethoxyvinyl glycine hydrochloride 2-AMINO-5-CHLOROPYRIMIDINE-4-CARBOXYLIC ACID 2-Aminobenzylchloride Difluorochloromethane 4-tert-Butoxy-6-chloropyrimidin-2-amine 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE 5-CHLORO-4-[(2-CHLOROBENZYL)SULFANYL]-6-METHYL-2-PYRIMIDINAMINE