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| | Hexadecyl trimethyl ammonium bromide Basic information |
| Product Name: | Hexadecyl trimethyl ammonium bromide | | Synonyms: | N-CETYL-N,N,N-TRIMETHYLAMMONIUM BROMIDE;N,N,N-TRIMETHYLTETRADECYLAMMONIUM BROMIDE;N-HEXADECYL-N,N,N-TRIMETHYLAMMONIUM BROMIDE;N-HEXADECYLTRIMETHYLAMMONIUM BROMIDE;PALMITYLTRIMETHYLAMMONIUM BROMIDE;TIMTEC-BB SBB008910;TRIMETHYLHEXADECYL-AMMONIUM BROMIDE;1-Hexadecanaminium,N,N,N-trimethyl-,bromide | | CAS: | 57-09-0 | | MF: | C19H42BrN | | MW: | 364.45 | | EINECS: | 200-311-3 | | Product Categories: | CETAB;Pharmaceutical raw materials;Organics;bc0001;57-09-0;Surfactants (for Biochemistry);Quaternary Ammonium Compounds;Cationic Surfactants (for Biochemistry);Biochemistry;Ammonium Bromides (Quaternary) | | Mol File: | 57-09-0.mol |  |
| | Hexadecyl trimethyl ammonium bromide Chemical Properties |
| Melting point | 248-251 °C(lit.) | | density | 1.1107 (rough estimate) | | bulk density | 390kg/m3 | | refractive index | 1.5260 (estimate) | | Fp | 244 °C | | storage temp. | Store below +30°C. | | solubility | H2O: 50 mg/mL | | form | powder | | color | white | | PH | 5.0-7.0 (25℃, 0.1M in H2O) | | Odor | Odorless | | PH Range | 5 - 7 | | Water Solubility | 13 g/L (20 ºC) | | Sensitive | Hygroscopic | | λmax | λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.05 | | Merck | 14,2025 | | BRN | 3598189 | | Stability: | Stable. Incompatible with strong oxidizing agents. Protect from moisture. | | Cosmetics Ingredients Functions | PRESERVATIVE
ANTISTATIC
SURFACTANT - EMULSIFYING
ANTIMICROBIAL | | Cosmetic Ingredient Review (CIR) | Hexadecyl trimethyl ammonium bromide (57-09-0) | | InChI | 1S/C19H42N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1 | | InChIKey | LZZYPRNAOMGNLH-UHFFFAOYSA-M | | SMILES | [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C | | CAS DataBase Reference | 57-09-0(CAS DataBase Reference) | | EPA Substance Registry System | Cetyl trimethyl ammonium bromide (57-09-0) |
| Hazard Codes | Xn,N | | Risk Statements | 22-37/38-41-50-50/53-36/37/38-48/22 | | Safety Statements | 26-39-61-37/39-60-36 | | RIDADR | UN 3077 9/PG 3 | | WGK Germany | 3 | | RTECS | BQ7875000 | | F | 3 | | TSCA | TSCA listed | | HazardClass | 9 | | PackingGroup | III | | HS Code | 29239000 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Dam. 1
Skin Irrit. 2
STOT RE 2 Oral
STOT SE 3 | | Toxicity | LD50 in mice, rats (mg/kg): 32.0, 44.0 i.v. (Isomaa, Bjondahl) |
| | Hexadecyl trimethyl ammonium bromide Usage And Synthesis |
| Chemical Properties | White powder. Soluble in water, alcohol,
and chloroform. | | Uses | antiinfectant | | Uses | Hexadecyltrimethylammonium Bromide (CTAB) is a cationic surfactant used as a template in the synthesis of Mesoporous γ-Fe2O3. | | Uses | A cationic detergent used in the isolation of high molecular weight DNA. | | Uses | cetrimonium bromide is a quaternary ammonium salt that can prevent the proliferation of bacteria, fungi, and yeast in cosmetic preparation, while also act as an emulsifying agent. | | Definition | ChEBI: The organic bromide salt that is the bromide salt of cetyltrimethylammonium; one of the components of the topical antiseptic cetrimide. | | General Description | Hexadecyltrimethylammonium bromide is a titrant for the potentiometric titration of perchlorate with ionselective electrodes. | | Biochem/physiol Actions | Hexadecyltrimethylammonium bromide also called cetyltrimethylammonium bromide (CTAB), is a cationic surfactant. CTAB is employed for extraction of DNA. CTAB method is efficient, cost and time effective for DNA extraction. CTAB is used as a shaping material and reducing agent for nanoparticle generation. | | Purification Methods | Crystallise it from EtOH, EtOH/*benzene or from wet acetone after extracting twice with pet ether. Shake it with anhydrous diethyl ether, filter and dissolve it in a little hot MeOH. After cooling in the refrigerator, the precipitate is filtered off at room temperature and re-dissolved in MeOH. Anhydrous ether is added and, after warming to obtain a clear solution, it is cooled and the crystalline material is collected. [Dearden & Wooley J Phys Chem 91 2404 1987, Hakemi et al. J Am Chem Soc 91 120 1987, Beilstein 4 IV 819.] | | References | [1] Liu, Tingting et al. “Hexadecyl trimethyl ammonium bromide assisted growth of NiCo2O4@reduced graphene oxide/ nickel foam nanoneedle arrays with enhanced performance for supercapacitor electrodes.” RSC Advances 7 (2022): 4029–4041. |
| | Hexadecyl trimethyl ammonium bromide Preparation Products And Raw materials |
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