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| | L-glutamic acid monoammonium Basic information |
| Product Name: | L-glutamic acid monoammonium | | Synonyms: | ammoniumglutaminat;mag;monoammoniumglutamate;monoammoniumsalt,l-glutamicaci;[S]-2-AMINOPENTANEDIOIC ACID MONOAMMONIUM SALT;(S)-2-AMINOPENTANEDIOIC ACID AMMONIUM SALT;L-GLUTAMIC ACID AMMONIUM SALT;L-GLUTAMIC ACID, MONOAMMONIUM SALT | | CAS: | 7558-63-6 | | MF: | C5H12N2O4 | | MW: | 164.16 | | EINECS: | 231-447-1 | | Product Categories: | | | Mol File: | 7558-63-6.mol |  |
| | L-glutamic acid monoammonium Chemical Properties |
| Melting point | 169 - 173°C | | storage temp. | −20°C | | solubility | Aqueous Acid (Slightly), Methanol (Very Slightly), Water (Slightly) | | form | White Crystalline Powder | | color | White to Off-White | | Odor | at 100.00%. odorless | | biological source | rat | | Stability: | Hygroscopic | | Major Application | cell analysis | | InChI | InChI=1/C5H9NO4.H3N/c6-3(5(9)10)1-2-4(7)8;/h3H,1-2,6H2,(H,7,8)(H,9,10);1H3/t3-;/s3 | | InChIKey | PHKGGXPMPXXISP-OQFXAWDINA-N | | SMILES | [C@@H](N)(C(=O)O)CCC(=O)O.N |&1:0,r| | | LogP | -1.435 (est) | | EPA Substance Registry System | L-Glutamic acid, monoammonium salt (7558-63-6) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | RTECS | MA1400000 | | TSCA | TSCA listed | | Storage Class | 13 - Non Combustible Solids |
| | L-glutamic acid monoammonium Usage And Synthesis |
| Description | Refer to monosodium glutamate. | | Description | L-Glutamic acid is a non-essential amino acid and the primary excitatory neurotransmitter in the CNS. It acts on ionotropic and metabotropic receptors to induce excitatory synaptic transmission and has roles in synaptic plasticity. Excessive release of L-glutamic acid induces excitotoxicity that is associated with various human diseases, including amyotrophic lateral sclerosis (ALS), stroke, Parkinson’s disease, Alzheimer’s disease, and Huntington’s disease. Excessive L-glutamic acid release, in its protonated glutamate form, also occurs during seizure activity and contributes to epileptogenesis and seizure-induced brain damage. | | Chemical Properties | White, basically odorless, easily flowing crystalline powder. It has special flavor. Easily soluble in water, almost insoluble in common organic solvents.5% aqueous solution Ph value is 6.0-7.0. | | Uses | L-Glutamic Acid Monoammonium Salt is a food additive; It can protect hypertensive rats from strokes. | | Uses | Monoammonium l-Glutamate is a flavor enhancer and salt substitute that is crystalline powder (white, free-flowing) and odorless. It is soluble in water, insoluble in common organic solvents, and is obtained by chemical synthesis. It is a low sodium alternative to monosodium glutamate. It is used in meats, soups, gravies, and sausage. It is also termed ammonium glutamate and monoammonium glutamate. | | Safety Profile | Moderately toxic by
intraperitoneal route. When heated to
decomposition it emits toxic fumes
including NOx and NH3. | | References | [1] S. G. Glutamic Acid, Twenty Years Later[J]. Journal of Nutrition, 2000, 130 4: Pages 901S-909S. DOI: 10.1093/jn/130.4.901s
[2] GREENAMYRE J T. The role of glutamate in neurotransmission and in neurologic disease.[J]. Archives of neurology, 1986, 43 10: 1058-1063. DOI: 10.1001/archneur.1986.00520100062016
[3] MELISSA BARKER-HALISKI H S W. Glutamatergic Mechanisms Associated with Seizures and Epilepsy.[J]. Cold Spring Harbor perspectives in medicine, 2015, 5 8: a022863. DOI: 10.1101/cshperspect.a022863 |
| | L-glutamic acid monoammonium Preparation Products And Raw materials |
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