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| | GLYCYL-L-GLUTAMIC ACID Basic information |
| | GLYCYL-L-GLUTAMIC ACID Chemical Properties |
| Melting point | 155-158 °C (dec.)(lit.) | | Boiling point | 342.66°C (rough estimate) | | density | 1.4123 (rough estimate) | | refractive index | 1.4880 (estimate) | | storage temp. | -20°C | | pka | 3.02±0.10(Predicted) | | form | powder to crystal | | color | White to Almost white | | Water Solubility | very faint turbidity | | InChI | 1S/C7H12N2O5/c8-3-5(10)9-4(7(13)14)1-2-6(11)12/h4H,1-3,8H2,(H,9,10)(H,11,12)(H,13,14)/t4-/m0/s1 | | InChIKey | IEFJWDNGDZAYNZ-BYPYZUCNSA-N | | SMILES | NCC(=O)N[C@@H](CCC(O)=O)C(O)=O | | CAS DataBase Reference | 7412-78-4(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29224985 | | Storage Class | 11 - Combustible Solids |
| | GLYCYL-L-GLUTAMIC ACID Usage And Synthesis |
| Uses | Glycyl-L-glutamic acid is a neurotrophic factor (NF) in vivo, and exerts function of maintenance of AChE content and activity. Glycyl-L-glutamic acid doesn’t act directly on AChE synthesis, and may prevent preganglionic neuronal degeneration[1][2]. | | Definition | ChEBI: A dipeptide formed from glycyl and L-glutamic acid residues. | | References | [1] Koelle GB, et al. Glycyl-L-glutamine, a precursor, and glycyl-L-glutamic acid, a neurotrophic factor for maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat in vivo. Proc DOI:10.1073/pnas.82.15.5213
[2] Yourick JJ, et al. Regeneration of acetylcholinesterase in clonal neuroblastoma-glioma hybrid NG108-15 cells after soman inhibition: effect of glycyl-L-glutamine. Cell Biol Toxicol. 1991 Jul;7(3):229-37. DOI:10.1007/BF00250977 |
| | GLYCYL-L-GLUTAMIC ACID Preparation Products And Raw materials |
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