- Ac-DEVD-pNA
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- $55.00
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2026-07-27
- CAS:189950-66-1
- Purity: 100.00%
- Supply Ability: 10g
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| | Ac-DEVD-PNA Basic information |
| Product Name: | Ac-DEVD-PNA | | Synonyms: | CASPASE 3 (APOPAIN) SUBSTRATE 1, CHROMOGENIC;CASPASE-3 SUBSTRATE VIII, WATER-SOLUBLE, COLORIMETRIC;CASPASE 3/CPP32 CHROMOGENIC SUBSTRATE;CASPASE-3 SUBSTRATE (CHROMOGENIC);CASPASE-3 SUBSTRATE I, COLORIMETRIC;CHROMOGENIC CASPASE 3 SUBSTRATE AC-DEVD-PNA;AC-ASP-GLU-VAL-ASP-PARANITROANILIDE;ACETYL-DEVD-PNA | | CAS: | 189950-66-1 | | MF: | C26H34N6O13 | | MW: | 638.58 | | EINECS: | | | Product Categories: | Caspase/Related Products;Pepetides;peptide | | Mol File: | 189950-66-1.mol |  |
| | Ac-DEVD-PNA Chemical Properties |
| Boiling point | 1191.1±65.0 °C(Predicted) | | density | 1.448±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMSO (Slightly), Methanol (Slightly, Heated) | | pka | 2.97±0.10(Predicted) | | form | powder | | color | white | | Water Solubility | Soluble in water (partly), dimethyl sulfoxide, buffer, pH 7, and acetonitrile:methanol (1:1) (1 mg/ml). | | Sequence | N-Acetyl-Asp-Glu-Val-Asp-p-Nitroanilide | | Stability: | Hygroscopic | | InChIKey | GGXRLUDNGFFUKI-ORGXJRBJSA-N | | SMILES | CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc(cc1)[N+]([O-])=O |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | Ac-DEVD-PNA Usage And Synthesis |
| Uses | N-Acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine is an para-nitro aniline chromophore cleaved by caspase. | | Uses | N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide is an chromogenic substrate for Caspase 3 and CCP-32. | | Uses | N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide has been used as a chromogenic substrates for determining caspase-3 and caspase-8 activities in liver tissue homogenates and caspase 3 activity in aortic vascular smooth muscle cells and neuroblastoma cell lines. | | Biochem/physiol Actions | Colorimetric substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase. | | IC 50 | Caspase-3; Caspase-7 |
| | Ac-DEVD-PNA Preparation Products And Raw materials |
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