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- 7-Methylindole
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-
2026-07-31
- CAS:933-67-5
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1000kgs
- 7-Methylindole
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- $9.00
-
2026-05-28
- CAS:933-67-5
- Min. Order: 1KG
- Purity: 99.9
- Supply Ability: 1 ton
- 7-Methylindole
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-
2026-01-29
- CAS:933-67-5
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 500kg
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| | 7-Methylindole Chemical Properties |
| Melting point | 80-84 °C (lit.) | | Boiling point | 266 °C (lit.) | | density | 1.0202 | | refractive index | 1.6070 (estimate) | | Fp | 266°C | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Crystalline | | pka | 17.30±0.30(Predicted) | | color | Off-White to Pale Beige | | Water Solubility | negligible | | Sensitive | Light Sensitive | | BRN | 111088 | | InChI | 1S/C9H9N/c1-7-3-2-4-8-5-6-10-9(7)8/h2-6,10H,1H3 | | InChIKey | KGWPHCDTOLQQEP-UHFFFAOYSA-N | | SMILES | Cc1cccc2cc[nH]c12 | | LogP | 2.560 | | CAS DataBase Reference | 933-67-5(CAS DataBase Reference) | | NIST Chemistry Reference | 1H-Indole, 7-methyl-(933-67-5) |
| Hazard Codes | Xi,Xn | | Risk Statements | 36/37/38-36-21/22 | | Safety Statements | 26-36-36/37/39 | | WGK Germany | 3 | | F | 13 | | Hazard Note | Light Sensitive/Irritant | | HS Code | 29309090 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 7-Methylindole Usage And Synthesis |
| Synthesis | 
Weigh 10 mmol of 2-methylaniline and 0.2 mmol of AlCl3 into a reaction flask, dissolve them in 100 mL of tetrahydrofuran, and add 30 mmol of ethylene oxide to the reaction flask at 0 °C. Maintain 0 °C and stir the reaction for 10 h. After separation and purification, N-hydroxyethyl-2-methylaniline (yield 83.1%) is obtained. Weigh 5 mmol of N-hydroxyethyl-2-methylaniline and 7.5 mmol of 2-methylaniline into a reaction flask, dissolve them in 200 mL of acetonitrile, add Sn/activated carbon supported catalyst, and stop the reaction after TLC detection of complete reaction of N-hydroxyethyl-2-methylaniline. After separation and purification, 7-methylindole was obtained (yield 64.3%). | | Uses | 7-Methylindole is a reactant in the synthesis of α-amino amides that are found in a variety of biological-active compounds. | | Chemical Properties | white to slightly beige shiny flakes | | Uses | 7-Methylindole is a reactant in the synthesis of α-amino amides that are found in a variety of biological-active compounds. | | Synthesis Reference(s) | Tetrahedron Letters, 30, p. 2129, 1989 DOI: 10.1016/S0040-4039(01)93730-X |
| | 7-Methylindole Preparation Products And Raw materials |
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