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| | 1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Basic information |
| Product Name: | 1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE | | Synonyms: | IBUPROFEN IMPURITY R;1,1-Bis(p-isobutylphenyl)ethane;IBuprofen Impurity 18;Ibuprofen EP Impurity R;1,1-Bis(p-isobutylphenyl)ethane(Ibuprofen EP Impurity R);Ibuprofen EP Impurity R：Ibuprofen Impurity R;1,1'-(Ethane-1,1-diyl)-4,4'-(2-meth;Benzene, 1,1'-ethylidenebis[4-(2-methylpropyl)- | | CAS: | 102120-87-6 | | MF: | C22H30 | | MW: | 294.47 | | EINECS: | | | Product Categories: | | | Mol File: | 102120-87-6.mol |  |
| | 1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Chemical Properties |
| Boiling point | 174-184 °C(Press: 2-3 Torr) | | density | 0.924±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | Acetonitrile (Slightly), Chloroform, Methanol (Slightly) | | form | Oil | | color | Colourless | | Major Application | pharmaceutical |
| WGK Germany | WGK 3 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Acute Tox. 4 Oral
Aquatic Chronic 4 |
| | 1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Usage And Synthesis |
| Uses | 1,1-Bis(p-isobutylphenyl)ethane (Ibuprofen EP Impurity R) is an impurity in the synthesis of Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. |
| | 1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Preparation Products And Raw materials |
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