DBCO-PEG1 manufacturers
- DBCO-PEG1
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2026-04-20
- CAS:1839049-33-0
- Purity:
- Supply Ability: 10g
- DBCO-C2-alcohol
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2025-06-07
- CAS:1839049-33-0
- Min. Order: 50mg
- Purity: >99.00%
- Supply Ability: 250mg
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| | DBCO-PEG1 Basic information |
| Product Name: | DBCO-PEG1 | | Synonyms: | DBCO-PEG1;DBCO-C2-alcohol;Dibenz[b,f]azocine-5(6H)-butanamide, 11,12-didehydro-N-(2-hydroxyethyl)-γ-oxo-;DBCO-C2-OH | | CAS: | 1839049-33-0 | | MF: | C21H20N2O3 | | MW: | 348.4 | | EINECS: | | | Product Categories: | | | Mol File: | 1839049-33-0.mol |  |
| | DBCO-PEG1 Chemical Properties |
| Boiling point | 716.8±60.0 °C(Predicted) | | density | 1.30±0.1 g/cm3(Predicted) | | solubility | Soluble in DMSO, DCM, DMF | | pka | 14.45±0.10(Predicted) |
| | DBCO-PEG1 Usage And Synthesis |
| Description | DBCO-C2-alcohol is a linker containing a DBCO moiety and a terminal primary hydroxyl group. DBCO group can react with azides in copper-free Click Chemistry reactions. The hydroxyl can react with a variety of functional groups. | | Uses | DBCO-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG1 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | DBCO-PEG1 Preparation Products And Raw materials |
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