- 2-Oxazolidone
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2026-06-30
- CAS:497-25-6
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1000kg
- 2-Oxazolidone
-
- $10.00
-
2026-05-28
- CAS:497-25-6
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 10 ton
- 2-Oxazolidone
-
- $10.00
-
2026-03-20
- CAS:497-25-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100 mt
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| | 2-Oxazolidone Basic information |
| | 2-Oxazolidone Chemical Properties |
| Melting point | 83-87 °C(lit.) | | Boiling point | 220 °C48 mm Hg(lit.) | | density | 1.2736 (rough estimate) | | refractive index | 1.4940 (estimate) | | Fp | 220°C/48mm | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly, Heated), Methanol (Slightly) | | pka | 12.78±0.20(Predicted) | | form | Crystals or Powder | | color | Off-white to yellow-beige | | Water Solubility | Soluble in water. | | BRN | 106251 | | InChI | 1S/C3H5NO2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5) | | InChIKey | IZXIZTKNFFYFOF-UHFFFAOYSA-N | | SMILES | O=C1NCCO1 | | CAS DataBase Reference | 497-25-6(CAS DataBase Reference) | | NIST Chemistry Reference | Oxazolidin-2-one(497-25-6) | | EPA Substance Registry System | 2-Oxazolidinone (497-25-6) |
| Hazard Codes | Xn,Xi | | Risk Statements | 22-36-43-40-36/37/38 | | Safety Statements | 26-36/37-37-36 | | WGK Germany | 3 | | RTECS | RQ2450000 | | TSCA | TSCA listed | | HS Code | 29322980 | | Storage Class | 13 - Non Combustible Solids | | Toxicity | TDLo orl-mus: 1000 mg/kg:ETA BCPCA62,168,59 |
| | 2-Oxazolidone Usage And Synthesis |
| Chemical Properties | off-white to yellow-beige crystals or powder | | Uses | As an oxazole derivative used as an antibiotic, 2-Oxazolidone is also used in the preparation of compounds with antitumor activity and as a metabolite of Furazolidone (F864100). | | Uses | An oxazole derivative used as an antibiotic. It is also used in the preparation of compounds with antitumor activity. A metabolite of Furazolidone (F864100). | | Definition | ChEBI: An oxazolidinone that is 1,3-oxazolidine with an oxo substituent at position 2. | | Safety Profile | Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx. | | Synthesis | 2-Oxazolidinone is synthesized by the following methods: 1) electrolytic cyclization and oxidation of hydroxyethyl formamide; 2) reaction of aminoethanol with CO2 gas; 3) reaction of epoxide with cyanuric acid or urea; 4) reaction of acrolein with isocyanate; 5) reaction of aziridine with CO2 gas; 6) reaction of -hydroxyethyl carbamate with urea; 7) reaction of aminoethanol with urea etc. | | Purification Methods | Crystallise it from *benzene, dichloroethane, CHCl3 or EtOH. It is a cyclic urethane, and as such it is not very stable. [Katritzky et al. J Chem Soc Perkin II 145 1990, Beilstein 27 H 135, 27 II 259, 27 III/IV 2516.] |
| | 2-Oxazolidone Preparation Products And Raw materials |
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