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| | L(+)-Lysine monohydrate Basic information |
| | L(+)-Lysine monohydrate Chemical Properties |
| Melting point | 212-214 °C | | alpha | 26.25 º (c=8, 6N HCl) | | bulk density | 366kg/m3 | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | H2O: soluble | | form | Crystalline Powder or Crystals | | color | White to yellow | | PH | 9-10.5 (20°C, 80g/L in H2O) | | biological source | non-animal source | | Optical Rotation | [α]20/D +22.5±1°, c = 2% in 6 M HCl | | Water Solubility | >1500 g/L (20 ºC) | | Sensitive | Air Sensitive & Hygroscopic | | Merck | 14,5636 | | BRN | 1722531 | | InChI | 1S/C6H14N2O2.H2O/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H2/t5-;/m0./s1 | | InChIKey | HZRUTVAFDWTKGD-JEDNCBNOSA-N | | SMILES | [H]O[H].NCCCC[C@H](N)C(O)=O | | CAS DataBase Reference | 39665-12-8(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 24/25-36/37/39-26 | | WGK Germany | 3 | | RTECS | OL5540000 | | TSCA | Yes | | HS Code | 29224100 | | Storage Class | 11 - Combustible Solids |
| | L(+)-Lysine monohydrate Usage And Synthesis |
| Chemical Properties | white to slightly yellow crystalline powder | | Uses | L-Lysine Monohydrate can be used to study the impacts of the disease from E.coli infection and benefits of preventive consumption of a stimulator of homeopathic immunity | | General Description | L-Lysine is an amino acid with a basic side chain and is amphipathic in nature. It has a protonated alkyl amino group and is fully protonated at physiological pH. L-lysine mainly participates in electrostatic interactions in proteins. | | Biochem/physiol Actions | L-Lysine is an essential proteinogenic α amino acid used in a wide range of applications including as a non-animal sourced supplement in cell culture media, a substrate of enzymes such as L-lysine oxidase (EC 1.4.3.14), a component of poly-lysine polymers, and a substrate for oxidation and glycation mechanism studies. | | in vivo | L-Lysine hydrate (40 μg/kg; p.o.) ameliorates arterial calcification in adenine rats and protects the femora from osteoporotic changes in adenine rats[1].
L-Lysine hydrate (10 and 400 mg/kg; i.g. and p.o.; Male mice) inhibits pancreatic tissue damage[2]. | Animal Model: | Male mice[2] | | Dosage: | 10 and 400 mg/kg | | Administration: | Intraperitoneal injection and oral administration; for 15 days | | Result: | Inhibited the release of the inflammatory cytokine IL-6 and enhance antioxidant activity. |
| | IC 50 | Microbial Metabolite; Human Endogenous Metabolite |
| | L(+)-Lysine monohydrate Preparation Products And Raw materials |
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