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| | 6,7-Dichloro-1,4-dihydro-2,3-quinoxalinedione Basic information |
| Product Name: | 6,7-Dichloro-1,4-dihydro-2,3-quinoxalinedione | | Synonyms: | 2,3-DIHYDROXY-6,7-DICHLOROQUINOXALINE;6,7-Dichloro-2,3-dihydroxyquinoxaline;6,7-Dichloro-1,4-dihydroquinoxaline-2,3-dione 98%;6,7-Dichloroquinoxaline-2,3(1H,4H)-dione;6,7-Dichloroquinoxaline-2,3-diol;DCQX;6,7-DICHLORO-2,3-QUINOXALINEDIONE;6,7-DICHLOROQUINOXALINE-2,3-DIONE | | CAS: | 25983-13-5 | | MF: | C8H4Cl2N2O2 | | MW: | 231.04 | | EINECS: | 202-887-1 | | Product Categories: | blocks;Heterocycles | | Mol File: | 25983-13-5.mol |  |
| | 6,7-Dichloro-1,4-dihydro-2,3-quinoxalinedione Chemical Properties |
| Melting point | 170-170.5 °C | | density | 1.590±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | pka | 8.45±0.20(Predicted) |
| Hazard Codes | Xi | | WGK Germany | 3 | | HS Code | 2933998090 |
| | 6,7-Dichloro-1,4-dihydro-2,3-quinoxalinedione Usage And Synthesis |
| Uses | 6,7-Dichloro-1,4-dihydroquinoxaline-2,3-dione is a potential antagonist of the glycine site on N-methyl-D-aspartate (NMDA) receptors and can be useful in the study of structure-activity relationships of quinoxaline derivatives as Gly/NMDA receptor antagonists. | | Definition | ChEBI: 6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione is a quinoxaline derivative. | | Synthesis | Step 1: Acetic anhydride (10 g, 98 mmol) was added dropwise to a solution of 3,4-dichloroaniline (10 g, 93.5 mmol) and triethylamine (10.4 g, 103 mmol) in 100 mL of anhydrous dichloromethane at 0 C. The mixture was stirred at room temperature for 6 hours and then concentrated. The residue was dissolved in ethyl acetate, washed with water and brine, dried, concentrated, and purified by recrystallization.
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| | 6,7-Dichloro-1,4-dihydro-2,3-quinoxalinedione Preparation Products And Raw materials |
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