- Britannilactone
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- $71.00
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2026-07-15
- CAS:33620-72-3
- Purity: 98.59%
- Supply Ability: 10g
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| | 1,6-Dihydroxyeriolanolide Basic information |
| Product Name: | 1,6-Dihydroxyeriolanolide | | Synonyms: | 1,6-Dihydroxyeriolanolide;Deacetylinulicin;Britannilactone (Desacetylinulicin);Desacetylinulicin;2(3H)-Benzofuranone, 3a,4,7,7a-tetrahydro-4-hydroxy-5-[(1S)-4-hydroxy-1-methylbutyl]-6-methyl-3-methylene-, (3aS,4S,7aR)- | | CAS: | 33620-72-3 | | MF: | C15H22O4 | | MW: | 266.33 | | EINECS: | | | Product Categories: | | | Mol File: | 33620-72-3.mol |  |
| | 1,6-Dihydroxyeriolanolide Chemical Properties |
| Melting point | 175.1-177.0℃ | | Boiling point | 477.4±45.0 °C(Predicted) | | density | 1.17±0.1 g/cm3 (20 ºC 760 Torr) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Cryst. | | pka | 13.71±0.60(Predicted) | | color | White to off-white |
| | 1,6-Dihydroxyeriolanolide Usage And Synthesis |
| Uses | Britannilactone(Desacetylinulicin) is a methanol extract of the dried flower of Inula britannica L.
IC50 value:
Target:
A bioassay-guided isolation of the chloroform fraction of the I. britannica using an in vitro melanogenesis inhibition assay led to the isolation of sesquiterpenes, 1-O-acetylbritannilactone (1), britannilactone (2) and neobritannilactone B (3). Compounds 1 and 2 significantly reduced melanin production in a dose-dependent manner with IC50 values of 13.3 and 15.5 μM, respectively [1]. | | References | [1] Choo SJ, et al. Hypo-pigmenting effect of sesquiterpenes from Inula britannica in B16 melanoma cells. Arch Pharm Res. 2014 May;37(5):567-74. DOI:10.1007/s12272-013-0302-4 |
| | 1,6-Dihydroxyeriolanolide Preparation Products And Raw materials |
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