- BrCH2CONH-PEG3-N3
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2025-06-07
- CAS:940005-81-2
- Min. Order: 500mg
- Purity: >98.00%
- Supply Ability: 500mg
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| | Bromoacetamido-PEG4-azido Basic information |
| Product Name: | Bromoacetamido-PEG4-azido | | Synonyms: | Bromoacetamido-PEG3-Azide;Bromoacetamido-PEG3-N3;Bromoacetamido-PEG4-azido;BrCH2CONH-PEG3-N3;N-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl]-2-bromoacetamide;Bromoacetamido-dPEG??-azide;Bromo-amido-peg3-azide;Bromoacetamide-PEG3-azide | | CAS: | 940005-81-2 | | MF: | C10H19BrN4O4 | | MW: | 339.19 | | EINECS: | | | Product Categories: | peg | | Mol File: | 940005-81-2.mol |  |
| | Bromoacetamido-PEG4-azido Chemical Properties |
| storage temp. | 2-8°C, sealed storage, away from moisture | | Appearance | Colorless to light yellow Liquid |
| | Bromoacetamido-PEG4-azido Usage And Synthesis |
| Description | Bromoacetamido-PEG3-azide is a crosslinking reagentwith 3 PEG units. The azide group enables Click Chemistry. Bromoacetamido is a very reactive group for nucleophilic substitution. The hydrophilic PEG spacer increases solubility in aqueous media. | | Uses | Bromoacetamido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromoacetamido-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Bromoacetamido-PEG4-azido Preparation Products And Raw materials |
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