|
|
| | 3-AMINOBENZOYLMETHYLAMIDE Basic information |
| | 3-AMINOBENZOYLMETHYLAMIDE Chemical Properties |
| Melting point | 119°C | | Boiling point | 346.7±25.0 °C(Predicted) | | density | 1.137±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | pka | 15.19±0.46(Predicted) | | form | powder to crystaline | | color | White to Light yellow to Light red | | CAS DataBase Reference | 25900-61-2(CAS DataBase Reference) |
| | 3-AMINOBENZOYLMETHYLAMIDE Usage And Synthesis |
| Synthesis | General procedure for the synthesis of 3-amino-N-methylbenzamide from N-methyl-3-nitrobenzamide: A mixture of N-methyl-3-nitrobenzamide (2.47 g, 13.71 mmol) with 10% Pd/C catalyst (0.5 g) in methanol (50 mL) was subjected to hydrogenation at room temperature and atmospheric pressure overnight. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the filtrate was subsequently concentrated. The resulting crude product was used directly in the subsequent reaction steps without further purification. (Yield: 2.06 g, 100%) | | References | [1] Patent: US2004/97493, 2004, A1. Location in patent: Page/Page column 24
[2] Patent: US2010/160323, 2010, A1. Location in patent: Page/Page column 54
[3] Journal of Chemical Research, 2006, # 4, p. 223 - 224
[4] Patent: US5589489, 1996, A
[5] Patent: EP2774918, 2014, A1. Location in patent: Paragraph 0126; 0133 |
| | 3-AMINOBENZOYLMETHYLAMIDE Preparation Products And Raw materials |
|