4-(Trifluoromethyl)benzoic acid

4-(Trifluoromethyl)benzoic acid Suppliers list

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Products Intro:	Product Name:4-(Trifluoromethyl)benzoic acid CAS:455-24-3

4-(Trifluoromethyl)benzoic acid manufacturers

4-(Trifluoromethyl)benzoic Acid: Synthesis, Antifungal Esters, and Analytical Applications
4-(Trifluoromethyl)benzoic acid synthesizes salicylanilide esters with antifungal activity, serves as a GC/MS internal standar....
Jun 27，2025

4-(Trifluoromethyl)benzoic acid Basic information

Product Name:	4-(Trifluoromethyl)benzoic acid
Synonyms:	4-(trifluoromethyl)-benzoicaci;Benzoic acid, 4-(trifluoromethyl)-;4-(TRIFLUOROMETHYL)BENZOIC ACID;A,A,A-TRIFLUORO-P-TOLUIC ACID;ALPHA,ALPHA,ALPHA-TRIFLUORO-P-TOLUIC ACID;PTF-BOA;RARECHEM AL BO 0066;P-CARBOXYBENZOTRIFLUORIDE
CAS:	455-24-3
MF:	C8H5F3O2
MW:	190.12
EINECS:	207-242-8
Product Categories:	Benzotrifluoride Series;Carboxylic Acids;Phenyls & Phenyl-Het;blocks;Carboxes;Boronic Acid series;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carboxylic Acids;Phenyls & Phenyl-Het;API intermediates;bc0001
Mol File:	455-24-3.mol

4-(Trifluoromethyl)benzoic acid Chemical Properties

Melting point	219-220 °C(lit.)
Boiling point	247°C 753mm
density	1.3173 (estimate)
Fp	247°C/753mm
storage temp.	Sealed in dry,Room Temperature
pka	3.69±0.10(Predicted)
form	Fine Crystalline Powder
color	White to slight gray
Water Solubility	Soluble in water.
BRN	2049241
InChI	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-5(2-4-6)7(12)13/h1-4H,(H,12,13)
InChIKey	SWKPKONEIZGROQ-UHFFFAOYSA-N
SMILES	C(O)(=O)C1=CC=C(C(F)(F)F)C=C1
CAS DataBase Reference	455-24-3(CAS DataBase Reference)
NIST Chemistry Reference	«ALPHA»,«alpha»,«alpha»-trifluoro-p-toluic acid(455-24-3)
EPA Substance Registry System	Benzoic acid, 4-(trifluoromethyl)- (455-24-3)

Safety Information

MSDS Information

4-(Trifluoromethyl)benzoic acid Usage And Synthesis

Uses	4-(Trifluoromethyl)benzaldehyde is a reactant that has been used in the preparation of N,N'-(Arylmethylene)bisamides with cytotoxic activity as anti cancer agents.
Chemical Properties	White to light yellow crystal powde
Uses	4-(Trifluoromethyl)benzoic acid was used in the synthesis of salicylanilide 4-(trifluoromethyl)benzoates viaN,N-dicyclohexylcarbodiimide coupling in dry N,N-dimethylformamide. It was used as internal standard during the ultra trace analysis of fluorinated aromatic carboxylic acids by GC/MS method.
Definition	ChEBI: A benzoic acid carrying a 4-trifluoromethyl substituent.

4-(Trifluoromethyl)benzoic acid Preparation Products And Raw materials

Raw materials	4-Methylbenzotrifluoride-->5,5-Dimethyl-2-[4-(trifluoromethyl)phenyl]-1,3,2-dioxaborinane-->trimethyl(4-(trifluoromethyl)phenyl)silane-->4-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER-->4-Bromobenzotrifluoride-->4-(Trifluoromethyl)benzyl alcohol-->4-Chlorobenzotrifluoride
Preparation Products	4-(TRIFLUOROMETHYL)PHENYL ISOCYANATE-->alpha,alpha,alpha-Trifluoro-o-toluoyl chloride-->4-Trifluoromethylsalicylic acid-->4'-(TRIFLUOROMETHYL)PROPIOPHENONE-->2-AMINO-4-(TRIFLUOROMETHYL)BENZOIC ACID-->N-(4-Methoxybenzyl)-4-(trifluoroMethyl)benzaMide, 97%

Tag:4-(Trifluoromethyl)benzoic acid(455-24-3) Related Product Information

o-Toluic acid 4-Bromomethylbenzoic acid 4-(Chloromethyl)benzoic acid Ethyl 2-(Chlorosulfonyl)acetate alpha,alpha,alpha-Trifluoro-o-toluoyl chloride p-Toluic acid Folic acid 3-(Trifluoromethyl)anisole m-Toluic acid 2,3,4-Trifluorobenzoic acid Methyl 4-trifluoromethylbenzoate 4-(Aminomethyl)benzoic acid 3-(Trifluoromethyl)benzaldehyde 2-(Trifluoromethyl)benzaldehyde 4-(Trifluoromethyl)benzylamine Citric acid α-Lipoic Acid 4-(TRIFLUOROMETHOXY)BENZOYL CHLORIDE