ML-109 manufacturers
- ML-109
-
- $72.00
-
2026-07-27
- CAS:1186649-91-1
- Purity: 98.63%
- Supply Ability: 10g
- ML-109
-
- $72.00
-
2026-07-27
- CAS:1186649-91-1
- Purity: 98.63%
- Supply Ability: 10g
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| Product Name: | ML-109 | | Synonyms: | ML-109;Acetamide, N-[4-[[2-methoxy-5-[1,2,3,4-tetrahydro-5-hydroxy-4-oxo-3-(phenylmethyl)-2-quinazolinyl]phenyl]methoxy]phenyl]-;N-[4-[[2-Methoxy-5-[1,2,3,4-tetrahydro-5-hydroxy-4-oxo-3-(phenylmethyl)-2-quinazolinyl]phenyl]methoxy]phenyl]acetamide;ML-109 (CID-25246343);TSH Receptor,Thyrotropin receptor,inhibit,ML-109,ML 109,Inhibitor,Thyroid-stimulating hormone Receptor,ML109;N-(4-((5-(3-Benzyl-5-hydroxy-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)-2-methoxybenzyl)oxy)phenyl)acetamide;N-(4-{[5-(3-benzyl-5-hydroxy-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)-2-methoxyphenyl]methoxy}phenyl)acetamide;ML-109, 10 mM in DMSO | | CAS: | 1186649-91-1 | | MF: | C31H29N3O5 | | MW: | 523.58 | | EINECS: | | | Product Categories: | API | | Mol File: | 1186649-91-1.mol |  |
| | ML-109 Chemical Properties |
| Boiling point | 810.1±65.0 °C(Predicted) | | density | 1.300±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:83.0(Max Conc. mg/mL);158.5(Max Conc. mM) | | form | Solid | | pka | 8.66±0.40(Predicted) | | color | White to light yellow |
| | ML-109 Usage And Synthesis |
| Uses | ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC50 of 40 nM. | | Definition | ChEBI: N-[4-[[5-[5-hydroxy-4-oxo-3-(phenylmethyl)-1,2-dihydroquinazolin-2-yl]-2-methoxyphenyl]methoxy]phenyl]acetamide is a member of quinazolines. | | References | [1] Neumann S, et al. Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12471-6. DOI:10.1073/pnas.0904506106 |
| | ML-109 Preparation Products And Raw materials |
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