t-Boc-Aminooxy-PEG7-amine manufacturers
|
| | t-Boc-Aminooxy-PEG7-amine Basic information |
| Product Name: | t-Boc-Aminooxy-PEG7-amine | | Synonyms: | t-Boc-Aminooxy-PEG7-amine;3,6,9,12,15,18,21,24-Octaoxa-2-azahexacosanoic acid, 26-amino-, 1,1-dimethylethyl ester;BocHNO-PEG7-CH2CH2NH2;Boc-NHO-PEG7-CH2CH2NH2 | | CAS: | 2226611-29-4 | | MF: | C21H44N2O10 | | MW: | 484.58 | | EINECS: | | | Product Categories: | | | Mol File: | 2226611-29-4.mol |  |
| | t-Boc-Aminooxy-PEG7-amine Chemical Properties |
| density | 1.096±0.06 g/cm3(Predicted) | | pka | 8.74±0.10(Predicted) |
| | t-Boc-Aminooxy-PEG7-amine Usage And Synthesis |
| Description | t-Boc-Aminooxy-PEG7-amine is an aqueous soluble reagent with a Boc-protected aminooxy group and an amino group. The amino group is reactive with carboxylic acids, activated NHS esters. The protected aminooxy can be deprotected under mild acidic conditions and then can react with an aldehyde or ketone group to form a stable oxime linkage. | | Uses | t-Boc-Aminooxy-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | t-Boc-Aminooxy-PEG7-amine Preparation Products And Raw materials |
|