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| | Boc-Aminooxy-PEG2-amine Basic information |
| Product Name: | Boc-Aminooxy-PEG2-amine | | Synonyms: | Boc-Aminooxy-PEG2-amine;t-Boc-Aminooxy-PEG2-amine;BOC-Aminooxy -PEG2-Amino;3,6,9-Trioxa-2-azaundecanoic acid, 11-amino-, 1,1-dimethylethyl ester;2-[2-[2-[(Boc-amino)oxy]ethoxy]ethoxy]ethanamine;t-Boc-Aminooxy-PEG2-amine boc;BocHNO-PEG2-CH2CH2NH2;Boc-Aminooxy-PEG2-C2-amine | | CAS: | 252378-69-1 | | MF: | C11H24N2O5 | | MW: | 264.32 | | EINECS: | | | Product Categories: | | | Mol File: | 252378-69-1.mol |  |
| | Boc-Aminooxy-PEG2-amine Chemical Properties |
| density | 1.077±0.06 g/cm3(Predicted) | | storage temp. | -20°C, stored under nitrogen | | solubility | Soluble in Water, DMSO, DMF, DCM | | pka | 8.74±0.10(Predicted) | | form | Viscous Liquid | | color | Colorless to light yellow |
| | Boc-Aminooxy-PEG2-amine Usage And Synthesis |
| Description | t-Boc-Aminooxy-PEG2-amine contains a Boc-protected aminooxy group and a free amino(NH2) group. Amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc- aminooxy can be deprotected under mild acidic conditions and then reacts with an aldehyde to form a linkage. | | Uses | Boc-Aminooxy-PEG2-C2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Boc-Aminooxy-PEG2-amine Preparation Products And Raw materials |
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