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| | Methyl allyl trisulfide Basic information |
| Product Name: | Methyl allyl trisulfide | | Synonyms: | ALLYL METHYL TRISULPHIDE;METHYL ALLYL TRISULFIDE;METHYL ALLYL TRISULPHIDE;1-Allyl-3-methyltrisulfane;Methyl 2-propenyl trisulfide;1-Methyl-3-allyl trisulfide;3-Methylsulfanyldisulfanylprop-1-ene;Allyl methyl pertrisulfide | | CAS: | 34135-85-8 | | MF: | C4H8S3 | | MW: | 152.3 | | EINECS: | 251-843-8 | | Product Categories: | sulfide Flavor | | Mol File: | 34135-85-8.mol |  |
| | Methyl allyl trisulfide Chemical Properties |
| Melting point | <25 °C | | Boiling point | bp0.05 28-30° | | density | 1.157±0.06 g/cm3(Predicted) | | FEMA | 3253 | ALLYL METHYL TRISULFIDE | | form | Liquid | | color | Colorless to light yellow | | Odor | at 0.10 % in propylene glycol. alliaceous creamy garlic onion | | Odor Type | sulfurous | | JECFA Number | 586 | | InChI | InChI=1S/C4H8S3/c1-3-4-6-7-5-2/h3H,1,4H2,2H3 | | InChIKey | JGMPRNFEEAJLAJ-UHFFFAOYSA-N | | SMILES | S(SC)SCC=C | | LogP | 2.72 | | NIST Chemistry Reference | Trisulfide, methyl 2-propenyl(34135-85-8) |
| | Methyl allyl trisulfide Usage And Synthesis |
| Chemical Properties | An oil-soluble component of garlic with a strong odor | | Occurrence | Reported found in garlic (Allium sativum L.), onion (Allium cepa L.), chive (Allium schoenoprasum L.), nira
(Allium tuberosum Rottl.), caucas (Allium victoralis L.), nobiru (Allium grayi Regal). | | Uses | Methyl allyl trisulfide is a volatile organic compound, and a component of the essential oils of garlic (Allium sativum L.). Methyl allyl trisulfide shows antiviral activity against HSV-1 in African green monkey kidney cell and antioxidant activity against DPPH radical in DMSO. | | in vivo | Allyl methyl trisulfide (AMS) (50-200 mg/kg, orally, daily, 30 days) has protective effect in STZ-induced hyperglycemia rats. It can lead to a significant decrease in the expression of blood glucose and pro-inflammatory markers TNF-α, IL-6, and NF-κB p65, while increasing plasma insulin levels, and has some antioxidant activity[1].
| Animal Model: | Male Wistar rats (170-190 g)[1] | | Dosage: | 50, 100 and 200 mg/kg | | Administration: | orally in the daily morning for 30 days | | Result: | Enhanced body, organ weight and reduced food, water intake.
Dose-dependently decreased plasma glucose and enhanced insulin.
Attenuated the oxidative stress stimulated by STZ in hepatocytes.
Increased activity of hepatotoxicity markers AST, ALT and ALP.
Significantly downregulated the expression of pro-inflammatory proteins, cytokines (TNF-α and IL-6) and transcription factors (NF-κB p65). |
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| | Methyl allyl trisulfide Preparation Products And Raw materials |
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