2-Hexanamidoacetic acid manufacturers
- Hexanoyl Glycine
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- $30.00 / 5mg
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2025-10-27
- CAS:24003-67-6
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | 2-Hexanamidoacetic acid Basic information |
| | 2-Hexanamidoacetic acid Chemical Properties |
| Melting point | 90-92°C | | Boiling point | 387.2±25.0 °C(Predicted) | | density | 1.074±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 3.60±0.10(Predicted) | | color | White to Off-White |
| | 2-Hexanamidoacetic acid Usage And Synthesis |
| Description | Hexanoyl glycine is an acylated amino acid that is used as a urinary biomarker for several indications. It is normally biosynthesized from hexanoyl-CoA and glycine by the mitochondrial enzyme glycine N-acyltransferase. Increased urinary excretion of hexanoyl glycine in humans is indicative of a deficiency in medium-chain acyl-CoA dehydrogenase. Increased urinary hexanoyl glycine can also be used as a biomarker for exposure to gamma radiation. Levels of hexanyl glycine can also be elevated during cancer, while they are decreased 20-fold in mice following treatment with the PPARα ligand Wy 14643. | | Chemical Properties | White Solid | | Uses | An acylaminoacid derivative as antipsychotic drug. | | Definition | ChEBI: An N-acylglycine in which the acyl group is specified as hexanoyl. | | References | [1] K Y TSERNG. Abnormal urinary excretion of unsaturated dicarboxylic acids in patients with medium-chain acyl-CoA dehydrogenase deficiency.[J]. Journal of Lipid Research, 1990, 31 5: 763-771.
[2] JOHN B TYBURSKI. Radiation metabolomics. 1. Identification of minimally invasive urine biomarkers for gamma-radiation exposure in mice.[J]. Radiation research, 2008, 170 1: 1-14. DOI: 10.1667/rr1265.1
[3] FEI LI. Metabolomics reveals that tumor xenografts induce liver dysfunction.[J]. Molecular & cellular proteomics?: MCP, 2013: 2126-2135. DOI: 10.1074/mcp.m113.028324
[4] YUEYING ZHEN. Metabolomic and genetic analysis of biomarkers for peroxisome proliferator-activated receptor alpha expression and activation.[J]. Molecular endocrinology, 2007: 2136-2151. DOI: 10.1210/me.2007-0150 |
| | 2-Hexanamidoacetic acid Preparation Products And Raw materials |
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