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| | 4-Ethylpyridine Basic information |
| | 4-Ethylpyridine Chemical Properties |
| Melting point | -91 °C | | Boiling point | 168 °C (lit.) | | density | 0.942 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.501(lit.) | | Fp | 118 °F | | storage temp. | Flammables area | | solubility | 107g/l | | form | Liquid | | pka | pK1:5.87(+1) (25°C) | | color | Clear colorless to yellow | | PH | 10 (100g/l, H2O, 20℃) | | Water Solubility | 34 g/L | | Merck | 14,3849 | | BRN | 106481 | | Henry's Law Constant | 1.2×100 mol/(m3Pa) at 25℃, Andon et al. (1954) | | Dielectric constant | 10.98 | | InChI | 1S/C7H9N/c1-2-7-3-5-8-6-4-7/h3-6H,2H2,1H3 | | InChIKey | VJXRKZJMGVSXPX-UHFFFAOYSA-N | | SMILES | CCc1ccncc1 | | LogP | 1.650 | | CAS DataBase Reference | 536-75-4(CAS DataBase Reference) | | NIST Chemistry Reference | 4-(C2H5)-pyridine(536-75-4) | | EPA Substance Registry System | 4-Ethylpyridine (536-75-4) |
| Hazard Codes | Xi,Xn | | Risk Statements | 10-36/37/38-20/21/22 | | Safety Statements | 26-36-36/37/39-16 | | RIDADR | UN 2924 3/PG 3 | | WGK Germany | 3 | | F | 8 | | TSCA | TSCA listed | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29333999 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3 |
| | 4-Ethylpyridine Usage And Synthesis |
| Chemical Properties |
clear colorless to yellowish liquid. Very powerful, sweet-green, in the pure state nauseating, in dilution slightly minty odour with sweet-herbaceous, mildly tarrypungent undertones. There is a certain similarity between the odour of mushrooms and dry-rotted wood. In suitable dilution, actually, a pleasant odour.
| | Uses |
4-Ethyl pyridine is used as a monomer in polymer
chemistry.
4-Ethylpyridine could find use in perfume compositions since it gives very interesting effects with Vetiver, Oakmoss, Hydroquinone dimethylether, Amylsalicylate, Coumarin, Lavender, etc., and in minute traces in certain florals, e.g. Hyacinth and Tuberose, also for “bouquetting” purposes in floral fragrances describing flowers from the floor of the woods, Muguet, Violet, etc. where the sweet-earthy, fungal notes can be applied artistically with pleasant effect.
| | Uses | 4-Ethylpyridine is used to study the influence of counter-anion concentration on analyte retention. | | Production Methods | 4-Ethylpyridine is produced by Wolff-Kishner reduction of 4-Acetylpyridine.
| | Synthesis Reference(s) | The Journal of Organic Chemistry, 22, p. 694, 1957 DOI: 10.1021/jo01357a607
Tetrahedron Letters, 26, p. 275, 1985 DOI: 10.1016/S0040-4039(01)80795-4 | | General Description | 4-Ethylpyridine undergoes metal-ligand interaction with Zn-porphyrin which can be studied by mass spectrometry. | | Contact allergens | 4-Ethyl-pyridine is used as a monomer in polymer
chemistry | | Purification Methods | Dry 4-ethylpyridine with BaO, and fractionally distil it. Also purified by converting to the picrate, recrystalising and the free base is regenerated and distilled. [Beilstein 20/6 V 10.] |
| | 4-Ethylpyridine Preparation Products And Raw materials |
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