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Hederacolchiside A1

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Hederacolchiside A1 manufacturers

  • Hederacolchiside A1
  • Hederacolchiside A1 pictures
  • 2023-02-24
  • CAS:106577-39-3
  • Min. Order: 5mg
  • Purity: ≥98%(HPLC)
  • Supply Ability: 10 g
  • Hederacolchiside A1
  • Hederacolchiside A1 pictures
  • $9.80
  • 2020-02-07
  • CAS:106577-39-3
  • Min. Order: 1KG
  • Purity: ＞98%HPLC
  • Supply Ability: 20 tons
Hederacolchiside A1 Basic information
Product Name:Hederacolchiside A1
Synonyms:Hederacolchiside A1;HEDERACOLCHISIDE A1;;Raddeanoside R13;Olean-12-en-28-oicacid, 3-[(O-6-deoxy-a-L-mannopyranosyl-(12)-O-[b-D-glucopyranosyl-(14)]-a-L-arabinopyranosyl)oxy]-, (3b)-;Oleanolic acid-3-O-β-D-rhamnopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→4)-]-α-L-arabinopyranoside，Hederacolchiside A1;Olean-12-en-28-oic acid, 3-[(O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-α-L-arabinopyranosyl)oxy]-, (3β)-;Hederacolchiside A1 USP/EP/BP;Oleanolic acid-3-O-β-D-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl-(1→4)--α-L-arabinopyranoside，Hederacolchiside A1
CAS:106577-39-3
MF:C47H76O16
MW:897.1
EINECS:
Product Categories:chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;reagent;standard substance;Triterpenoids
Mol File:106577-39-3.mol
Hederacolchiside A1 Structure
Hederacolchiside A1 Chemical Properties
Melting point 253-255℃ (methanol , water )
Boiling point 967.2±65.0 °C(Predicted)
density 1.36±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 4°C, protect from light
solubility Soluble in DMSO
pka4+-.0.70(Predicted)
form Solid
color White to off-white
Cosmetics Ingredients FunctionsSKIN CONDITIONING
Safety Information
MSDS Information
Hederacolchiside A1 Usage And Synthesis
UsesHederacolchiside A1, isolated from Pulsatilla chinensis, suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway[1]. Hederacolchiside A1 has antischistosomal activity, affecting parasite viability both in vivo and in vitro[2].
in vivo

hederacolchiside A1 (3.0, 4.5, and 6.0mg/kg, ip) can significantly inhibit the weight of tumor in an H22 xenograft model[1].
Hederacolchiside A1 (3.25, 7.5, and 15.0mg/kg, ig) can significantly inhibit the weight of tumor in nude mice xenograft tumor models using human breast carcinoma MCF-7 cells[1].

IC 50Schistosome; PI3K; mTOR
References[1] Yan-Er Wang, et al. Hederacolchiside A1 suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway. Chinese Herbal Medicines.Volume 10, Issue 2, April 2018, Pages 215-222
[2] Kang N, et al. Antischistosomal Properties of Hederacolchiside A1 Isolated from Pulsatilla chinensis. Molecules. 2018 Jun 13;23(6). DOI:10.3390/molecules23061431
Hederacolchiside A1 Preparation Products And Raw materials
Tag:Hederacolchiside A1(106577-39-3) Related Product Information
V Pulchinenoside B Scabioside C Lup-20(29)-en-28-oic acid, 3-[β-D-glucopyranosyl(1→4)[a-L-rhaMnopyranosyl) (1→2)-a -L-arabinopyranosyl]oxy], (3β,4a)-) Hederagenin 3-O-α-L-rhaMnopyranosyl(1→2)-(β-D-glucopyranosyl(1→4))-α-L-arabinopyranoside V Hederacolchiside E PULCHINENOSIDE B4 Anemoside A3 Pulchinenoside A3