| Company Name: |
Energy Chemical |
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400-0056266 |
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sales8178@energy-chemical.com |
1-Boc-3,5-dimethyl-piperazine manufacturers
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| Product Name: | 1-Boc-3,5-dimethyl-piperazine | | Synonyms: | (3R,5S)-3,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-BOC-CIS-3,5-DIMETHYL-PIPERAZINE;CIS-3,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;5-DiMethyl-piperazine-1-carboxylic acid tert-butyl ester;cis-3;1-Piperazinecarboxylic acid, 3,5-diMethyl-, 1,1-diMethylethyl ester, (3R,5S)-;(3R,5S)-rel-tert-Butyl 3,5-diMethylpiperazine-1-carboxylate;Cytokine-inducible SH2-containing protein-3 | | CAS: | 129779-30-2 | | MF: | C11H22N2O2 | | MW: | 214.31 | | EINECS: | | | Product Categories: | | | Mol File: | 129779-30-2.mol |  |
| | 1-Boc-3,5-dimethyl-piperazine Chemical Properties |
| Melting point | 70-71° | | Boiling point | 279.7±15.0℃ (760 Torr) | | density | 0.970±0.06 g/cm3 (20 ºC 760 Torr) | | Fp | 123.0±20.4℃ | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | pka | 8.58±0.60(Predicted) | | form | solid | | Appearance | White to off-white Solid | | InChI | InChI=1/C11H22N2O2/c1-8-6-13(7-9(2)12-8)10(14)15-11(3,4)5/h8-9,12H,6-7H2,1-5H3/t8-,9+ | | InChIKey | NUZXPHIQZUYMOR-DTORHVGONA-N | | SMILES | N1(C(OC(C)(C)C)=O)C[C@H](C)N[C@H](C)C1 |&1:9,12,r| |
| Hazard Codes | N | | Risk Statements | 36/37/38-50 | | Safety Statements | 26-61 | | RIDADR | UN3077 | | WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | 1-Boc-3,5-dimethyl-piperazine Usage And Synthesis |
| Uses | 1-Boc-cis-3,5-dimethyl-piperazine is used in the identification of 7-(3-(Piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives as highly potent, selective and orally bioavailable PI3Kδ inhibitors. | | Description | 1-BOC-3,5- dimethylpiperazine is a heterocyclic derivative and can be used as pharmaceutical intermediates. | | Uses | 1-Boc-cis-3,5-dimethyl-piperazine is used in the identification of 7-(3-(Piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives as highly potent, selective and orally bioavailable PI3Kδ inhibitors. | | Description | SOCS3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 262 amino acids (1-225 a.a) and having a molecular mass of 29kDa.SOCS3 is fused to a 37 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. | | Source | Escherichia Coli | | Background | Suppressor of Cytokine Signaling 3, also known as SOCS3 belongs to the SOCS family; in addition SOCS3 is a member of the STAT-induced STAT inhibitor (SSI). The SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of SOCS3 is induced by different cytokines, including IL6 and IL10. SOCS3 can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of SOCS3 have shown the roles of SOCS3 in the negative regulation of fetal liver hematopoiesis, and placental development. |
| | 1-Boc-3,5-dimethyl-piperazine Preparation Products And Raw materials |
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