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| | Dibucaine hydrochloride Basic information |
| Product Name: | Dibucaine hydrochloride | | Synonyms: | 2-butoxy-n-(2-(diethylamino)ethyl)-4-quinolinecarboxamidmonohydrochlorid;Dibucaine (Cinchocaine) HCl;2-butoxy-n-(2-(diethylamino)ethyl)-cinchoninamidmonohydrochloride;2-butoxy-n-(2-diethylaminoethyl)cinchoninicacidamidehydrochloride;2-n-butoxy-n-(2-diethylaminoethyl)cinchoninamidehydrochloride;4-Quinolinecarboxamide,2-butoxy-N-[2-(diethylamino)ethyl]-,monohydrochloride;benzolin(localanesthetic);butoxycinchoninicaciddiethylethylenediamidehydrochloride | | CAS: | 61-12-1 | | MF: | C20H30ClN3O2 | | MW: | 379.92 | | EINECS: | 200-498-1 | | Product Categories: | API;NUPERCAINAL;Other APIs;Amines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API | | Mol File: | 61-12-1.mol |  |
| | Dibucaine hydrochloride Chemical Properties |
| Melting point | 99-101 °C(lit.) | | density | 1.1338 (rough estimate) | | refractive index | 1.5400 (estimate) | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | color | Hygroscopic crystals | | PH | pH(20g/l,25℃) : 5.0～6.0 | | Water Solubility | Freely soluble in water, alcohol, acetone, or chloroform | | Merck | 13,3057 | | Stability: | Stable. Incompatible with strong oxidizing agents. Protect from moisture. | | Major Application | forensics and toxicology
pharmaceutical (small molecule) | | InChI | InChI=1S/C20H29N3O2.ClH/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3;/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24);1H | | InChIKey | IVHBBMHQKZBJEU-UHFFFAOYSA-N | | SMILES | C12C=CC=CC1=NC(OCCCC)=CC=2C(=O)NCCN(CC)CC.Cl | | CAS DataBase Reference | 61-12-1(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 22-41 | | Safety Statements | 26-39 | | WGK Germany | 3 | | RTECS | GD3325000 | | HS Code | 2933492250 | | Storage Class | 11 - Combustible Solids | | Toxicity | eye-rbt 2% SEV ARZNAD 8,181,58 |
| | Dibucaine hydrochloride Usage And Synthesis |
| Chemical Properties | white powder | | Uses | Anesthetic (local). | | Uses | Cinchocaine is used as an anaesthetic agent for spinal anaesthesia; a component in rectal medications used in inflammation of the
anus and for the symptomatic treatment of hemorrhoids and fissures in the anus; local anesthetic agent. | | Uses | Dibucaine HCl is an amide-like quinoline derivative and is one of the most potent
and longest acting of the commonly used local anesthetics. | | Definition | ChEBI: The monohydrochloride salt of cinchocaine. It is used in creams, ointments and suppositories for temporary relief of pain and itching associated with skin and anorectal conditions. | | Brand name | Nupercaine (Novartis). | | Biological Activity | Potent, long-acting local anesthetic | | Contact allergens | Dibucaine hydrochloride is an amide group local anesthetic
that can induce allergic contact dermatitis. | | Safety Profile | Poison by ingestion,subcutaneous, intravenous, intraspinal, parenteral, andintraperitoneal routes. Mutation data reported. A severeeye irritant. A local anesthetic. When heated todecomposition it emits very toxic fumes of HCl and NOx |
| | Dibucaine hydrochloride Preparation Products And Raw materials |
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