HOOCCH2CH2-PEG16-CH2CH2COOH manufacturers
- Bis-PEG17-acid
-
-
2025-06-07
- CAS:2226897-74-9
- Min. Order: 250mg
- Purity: >98.00%
- Supply Ability: 250mg
|
| | HOOCCH2CH2-PEG16-CH2CH2COOH Basic information |
| Product Name: | HOOCCH2CH2-PEG16-CH2CH2COOH | | Synonyms: | HOOCCH2CH2-PEG16-CH2CH2COOH;4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52-Heptadecaoxapentapentacontanedioic acid;Di-Acid-PEG17;HOOCCH2CH2O-PEG16-CH2CH2COOH/4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52-Heptadecaoxapentapentacontanedioic acid;COOH-PEG17-CH2CH2COOH | | CAS: | 2226897-74-9 | | MF: | C38H74O21 | | MW: | 866.98 | | EINECS: | | | Product Categories: | | | Mol File: | 2226897-74-9.mol |  |
| | HOOCCH2CH2-PEG16-CH2CH2COOH Chemical Properties |
| storage temp. | 2-8°C, sealed storage, away from moisture | | form | Solid | | color | Off-white to light yellow |
| | HOOCCH2CH2-PEG16-CH2CH2COOH Usage And Synthesis |
| Uses | Bis-PEG17-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | Biological Activity | Bis-PEG17-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | IC 50 | PEGs | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | HOOCCH2CH2-PEG16-CH2CH2COOH Preparation Products And Raw materials |
|