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| | DL-Adrenaline hydrochloride Basic information |
| Product Name: | DL-Adrenaline hydrochloride | | Synonyms: | (±)-4-[1-hydroxy-2-(methylamino)ethyl]pyrocatechol hydrochloride;Adrenaline Hcl， racepinephrine hcl;(±)-Epinephrine hydrochloride,(±)-Adrenalin, 4-(1-Hydroxy-2-[methylamino]ethyl)-1,2-benzenediol hydrochloride;Racepinephrine/Adrenaline HCL;Adrenalin HCL;1,2-Benzenediol, 4-1-hydroxy-2-(methylamino)ethyl-, hydrochloride;rs-epinephrine hcl;RACEPINEPHRINEHYDROCHLORIDE,USP | | CAS: | 329-63-5 | | MF: | C9H14ClNO3 | | MW: | 219.67 | | EINECS: | 206-346-0 | | Product Categories: | API;329-63-5 | | Mol File: | 329-63-5.mol |  |
| | DL-Adrenaline hydrochloride Chemical Properties |
| Melting point | 157° | | storage temp. | 2-8°C | | solubility | H2O: >50 mg/mL | | form | A crystalline solid | | Water Solubility | H2O: 50mg/mL | | Merck | 14,3619 | | Stability: | Stable, but light sensitive. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents. | | InChI | InChI=1S/C9H13NO3.ClH/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;/h2-4,9-13H,5H2,1H3;1H | | InChIKey | ATADHKWKHYVBTJ-UHFFFAOYSA-N | | SMILES | C1(C(O)CNC)=CC=C(O)C(O)=C1.Cl | | CAS DataBase Reference | 329-63-5(CAS DataBase Reference) | | EPA Substance Registry System | (+-)-Epinephrine hydrochloride (329-63-5) |
| Hazard Codes | T | | Risk Statements | 24/25-36/37/38 | | Safety Statements | 26-36/37-45 | | RIDADR | UN 2811 6.1/PG 2 | | WGK Germany | 3 | | RTECS | DO3330000 | | TSCA | TSCA listed | | HazardClass | 6.1(a) | | PackingGroup | II | | HS Code | 2937901500 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1 |
| | DL-Adrenaline hydrochloride Usage And Synthesis |
| Chemical Properties | solid | | Uses | bronchodilatator, | | Uses | An adrenergic receptor agonist. | | Uses | (±)-Epinephrine hydrochloride has been used:
- in the induction of renalase expression in Human renal proximal tubular epithelial cells
- in the infusion studies to test its effect on heart rate and eye temperature measurements in bull
- as a medium supplement for the stimulation of endothelial progenitor cells
| | General Description | Epinephrine (adrenalin) is synthesized from norepinephrine (noradrenalin) by the action of the enzyme phenylethanolamine N-methyltransferase. Epinephrine comprises 5%-10% of the total catecholamines in the central nervous system. It is a mixed α/β-adrenergic receptor agonist and stimulates these receptors. Their site of synthesis is adrenal medulla and it travels through the vascular systems. Its breakdown occurs in the central nervous system (CNS), liver and kidney. | | Biochem/physiol Actions | Epinephrine improves systemic pressure during cardiopulmonary resuscitation and is used post cardiac arrest. The levels of epinephrine increases during trauma, sepsis and hypoglycemia resulting in increased cardiac rate and contractility. It is used in the treatment of acute anaphylaxis. Use of epinephrine hydrochloride enables dilation of pupil during intraocular lens (IOL) implantation surgery. |
| | DL-Adrenaline hydrochloride Preparation Products And Raw materials |
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