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3-Chloro-2,4-difluoronitrobenzene

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3-Chloro-2,4-difluoronitrobenzene manufacturers

3-Chloro-2,4-difluoronitrobenzene Basic information
Synthesis
Product Name:3-Chloro-2,4-difluoronitrobenzene
Synonyms:3-Chloro-2,4-difluoronitrobenzene 97%, 4-difluoronitrobenzene 97%;3-Chloro-2,4-difluoronitrobenzene 97%;3-Chloro-2,4-difluoronitrobenzene97%;6014 2,4-DIFLUORO-3-CHLORO NITRO BENZENE;2,4-Difluoro-3-chloronitrobnzene;2,4-difluro-3-chloronitrobenzene;2,4-DIFLUORO-3-CHLORONITROBENZENE;2-CHLORO-1,3-DIFLUORO-4-NITRO-BENZENE
CAS:3847-58-3
MF:C6H2ClF2NO2
MW:193.54
EINECS:411-980-8
Product Categories:Fluorine series;Aromatic Halides (substituted)
Mol File:3847-58-3.mol
3-Chloro-2,4-difluoronitrobenzene Structure
3-Chloro-2,4-difluoronitrobenzene Chemical Properties
Melting point 41-43°C
Boiling point 243.0±35.0 °C(Predicted)
density 1.591±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility soluble in Methanol
form powder to crystal
color White to Light yellow
InChIInChI=1S/C6H2ClF2NO2/c7-5-3(8)1-2-4(6(5)9)10(11)12/h1-2H
InChIKeyCTVBVNKEMCGZDF-UHFFFAOYSA-N
SMILESC1(F)=CC=C([N+]([O-])=O)C(F)=C1Cl
CAS DataBase Reference3847-58-3(CAS DataBase Reference)
Safety Information
Hazard Codes C,N
Risk Statements 20/21/22-50/53-43-34-22
Safety Statements 36/37/39-45-61-60-28-26-22
RIDADR 1759
Hazard Note Corrosive
HazardClass 8
PackingGroup II
HS Code 2904990090
MSDS Information
3-Chloro-2,4-difluoronitrobenzene Usage And Synthesis
Synthesis

Becher et al. reported that 3-chloro-2,4-difluoronitrobenzene can be obtained by reacting 2,3,4-trichloronitrobenzene with potassium fluoride.

Synthesis of 3847-58-3

Chemical Propertieslight yellow crystal powde
Uses3-Chloro-2,4-difluoronitrobenzene is a pharmaceutical intermediate, which is reported in the literature to be used for the preparation of LSD1 inhibitors and selective HER2 inhibitors.
3-Chloro-2,4-difluoronitrobenzene Preparation Products And Raw materials
Preparation ProductsRUFLOXACIN-->7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 10-chloro-9-fluoro-2,3-dihydro-3-methyl-7-oxo-
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