HYOSCINE HYDROCHLORIDE manufacturers
- HYOSCINE HYDROCHLORIDE
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- $1.00 / 1KG
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2019-12-23
- CAS:55-16-3
- Min. Order: 1KG
- Purity: 98% HPLC
- Supply Ability: 10t
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| | HYOSCINE HYDROCHLORIDE Basic information |
| Product Name: | HYOSCINE HYDROCHLORIDE | | Synonyms: | SCOPINE TROPATE HYDROCHLORIDE;SCOPINE TROPATE;(-)-SCOPOLAMINE HYDROCHLORIDE;SCOPOLAMINE HYDROCHLORIDE;HYOSCINE HYDROCHLORIDE;0(sup2,4))non-7-ylester,hydrochloride,(7(s)-(1-alpha,2-beta,4-beta,5-alpha;5-alpha-h-tropan-3-alpha-ol,6-beta,7-beta-epoxy-1-alpha-(-)-tropate(est;chlorhydratedescopolamine | | CAS: | 55-16-3 | | MF: | C17H22ClNO4 | | MW: | 339.81 | | EINECS: | 200-225-6 | | Product Categories: | Pyrrolidines ,Pyrroles | | Mol File: | 55-16-3.mol |  |
| | HYOSCINE HYDROCHLORIDE Chemical Properties |
| Melting point | 200° | | Fp | 77 °C | | storage temp. | -20°C | | solubility | H2O: 50 mg/mL | | form | powder | | color | white | | Optical Rotation | [α]25/D ~ 27°, c = 1 in H2O(lit.) | | Water Solubility | H2O: 50mg/mL | | BRN | 4168778 | | CAS DataBase Reference | 55-16-3(CAS DataBase Reference) |
| | HYOSCINE HYDROCHLORIDE Usage And Synthesis |
| Uses | Antiemetic;Non-selective muscarinic antagonist | | Biochem/physiol Actions | Competitive nonselective muscarinic acetylcholine antagonist. Scopolamine-induced amnesia in laboratory animals is a commonly-used model of memory deficit. | | in vivo | Scopolamine induces memory impairment associated with attenuation of cholinergic neurotransmission, as well as an increases of processes connected with oxidative stress in the brain[3]. | Animal Model: | Naive male Swiss mice weighing 20-25[3] | | Dosage: | 1 mg/kg | | Administration: | Administered intraperitoneally (i.p.); to measure the memory acquisition processes, Scopolamine was administered 20 min before the pretest; to measure the memory consolidation processes, Scopolamine was administered immediately after the pretest | | Result: | In scopolamine-treated group, there was a significant decrease in the index of latency (IL) value as compared with the saline-treated mice, indicating that scopolamine at the used dose impaired acquisition of memory and learning. |
| | IC 50 | 5-HT3 Receptor: 2.09 μM (IC50) |
| | HYOSCINE HYDROCHLORIDE Preparation Products And Raw materials |
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