- Orthanilamide
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- $138.00
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2026-05-11
- CAS:3306-62-5
- Purity: 99.72%
- Supply Ability: 10g
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| | 2-Aminobenzenesulfonamide Basic information |
| | 2-Aminobenzenesulfonamide Chemical Properties |
| Melting point | 155-157 °C(lit.) | | Boiling point | 392.7±44.0 °C(Predicted) | | density | 1.3250 (rough estimate) | | refractive index | 1.6490 (estimate) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | DMSO (Sparingly), Methanol (Slightly) | | pka | 10.29±0.60(Predicted) | | form | Solid | | color | Off-White to Beige | | Water Solubility | 6.655g/L(24 ºC) | | InChI | InChI=1S/C6H8N2O2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,7H2,(H2,8,9,10) | | InChIKey | YAZSBRQTAHVVGE-UHFFFAOYSA-N | | SMILES | C1(S(N)(=O)=O)=CC=CC=C1N | | CAS DataBase Reference | 3306-62-5(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 36/37/39-26-22-36 | | WGK Germany | 3 | | RTECS | DA9449000 | | Hazard Note | Irritant | | HS Code | 29350090 | | Storage Class | 11 - Combustible Solids |
| | 2-Aminobenzenesulfonamide Usage And Synthesis |
| Chemical Properties | white to pale cream crystalline powder or crystals | | Uses | Diuretic;Inhibitor of carbonic anhydrase B | | Definition | ChEBI: 2-aminobenzenesulfonamide is a sulfonamide and a member of benzenes. | | Synthesis | General procedure for the synthesis of o-aminobenzenesulfonamide from 2-nitrobenzenesulfonamide: 2-nitrobenzenesulfonamide (80.0 g, 0.58 mol) was dissolved in methanol in the presence of a Pd/C catalyst (10.0 g, 13% w/w) to prepare a solution with a mass concentration of 10%. The hydrogenation reaction was carried out at 50 psi hydrogen pressure and 60°C and the reaction was continued overnight. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to give 60 g of off-white solid o-aminobenzenesulfonamide in 95% yield. | | IC 50 | CA Ⅸ | | Solubility in organics | 2-Aminobenzenesulfonamide is freely soluble in water, glacial acetic acid, ethyl alcohol, acetone, and methanol; insoluble in benzene.
| | References | [1] Patent: CN104761514, 2016, B. Location in patent: Paragraph 0028-0030
[2] Tetrahedron Letters, 2001, vol. 42, # 33, p. 5601 - 5603
[3] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 7, p. 2455 - 2478
[4] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 17, p. 5647 - 5647
[5] Bihang till Svenska Vet.-Akad. Handlingar, vol. 27, p. II, No. 1, S. 4 |
| | 2-Aminobenzenesulfonamide Preparation Products And Raw materials |
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