GABAA receptor agent 4 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-27 |
Product Details
| Product Name: GABAA receptor agent 4 | CAS No.: 2035203-91-7 |
| Supply Ability: 10g | Release date: 2025/10/27 |
Product Introduction
Bioactivity
| Name | GABAA receptor agent 4 |
| Description | GABAA receptor agent 4 (compound 1e) is a potent antagonist of γ-GABAAR, exhibiting a Ki of 0.18 µM, and demonstrates immunomodulatory potential by effectively rescuing the inhibition of T cell proliferation [1]. |
| In vitro | Compound 1e, a GABAA receptor antagonist, exhibits varying inhibitory concentrations (IC50s) across subtypes: 4.95 μM (α1β2δ), 0.195 μM (α4β1δ), 0.250 μM (α4β2δ), 1.95 μM (α6β2δ), 2.18 μM (α1β2γ2), 7.56 μM (α2β2γ2), 0.56 μM (α3β2γ2), and 0.54 μM (α5β2γ2) [1]. Additionally, at a concentration of 50 μM over 96 hours, Compound 1e counteracts alprazolam-induced proliferation inhibition in both human PBMC and mouse splenocyte populations, demonstrating minimal cellular toxicity [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | Compound PDK0243 | p-Hydroxybenzaldehyde | Urethane | Baicalin | Penicillin G sodium salt | DL-Pyroglutamic acid | Valproic Acid | Halothane | Chlorothymol | (-)-α-Pinene | Dihydromyricetin | Methionine |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $1980.00/50mg |
VIP4Y
|
TargetMol Chemicals Inc.
|
2025-10-27 | |
| $36.00/1mg |
VIP6Y
|
TargetMol Chemicals Inc.
|
2025-10-26 | |
| $10.00/10KG |
VIP1Y
|
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
|
2025-06-18 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
INQUIRY