基本描述
产品名称：胶原蛋白酶 来源于溶组织梭菌(纯化)
规格或纯度：EnzymoPure™, 天然, ≥500 units/mg dry weight
产品介绍：
Crude collagenase preparations contain several isoforms of two different collagenases, a sulfhydryl protease, clostripain, a trypsin-like enzyme, and an aminopeptidase. This combination of collagenolytic and proteolytic activities is effective at breaking down intercellular matrices, the essential part of tissue dissociation. One component of the complex is a hydrolytic enzyme which degrades the helical regions in native collagen preferentially at the Y-Gly bond in the sequence Pro-Y-Gly-Pro, where Y is most frequently a neutral amino acid. This cleavage yields products susceptible to further peptidase digestion. Crude collagenase is inhibited by metal chelating agents such as cysteine, EDTA or o-phenanthroline but not DFP. It is also inhibited by α2-macroglobulin, a large plasma glycoprotein. Ca2+ is required for enzyme activity. Particular enzymatic profiles of each collagenase have been correlated with the tissues from which the cells for study were obtained (or with the uses to which the cells are put) and as a result of the correlations several types of crude collagenases have been established by Aladdin: Types 1, 2, 3, and 4.This collagenase has been tested with cell lines to verify the product is not cytotoxic. Collagenase is typically used to digest the connective components in tissue samples to liberate individual cells. The concentration for cartilage dispersal is 1-2 mg/ml, but literature searches should be performed for species specific and/or tissue specific concentrations.
生物活性：≥500 units/mg dry weight
Accession #：Q46085,Q9X721
级别：天然, EnzymoPure™
产品规格参数
浓度：≥500 units/mg dry weight
储存条件：2-8°C储存
运输条件：低温运输
CAS编号和信息：9001-12-1
酶学委员会编号：EC 3.4.24.3
单位定义：One Unit releases one micromole of L-leucine equivalents from collagen in 5 hours at 37°C, pH 7.5.
功能和特点
Accession #：Q46085,Q9X721
生物活性：≥500 units/mg dry weight
查看阿拉丁官网此产品相关对应页面：https://www.aladdin-e.com/zh_cn/C128695.html
关键字： 梭菌肽酶 A ; 胶原酶;Collagenase I ; Collagenase Type II
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