AF12198
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- $110 - $2384
- Product name: AF12198
- CAS: 185413-30-3
- MF: C96H123N19O22
- MW: 1895.12
- EINECS:
- MDL Number:MFCD02259571
- Synonyms:AF12198;AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-AZE-TYR-ALA-LEU-PRO-LEU-NH2;AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-L-AZETIDINE-2-CARBONYL-TYR-ALA-LEU-PRO-LEU-NH2;AC-PHE-GLU-TRP-THR-PRO-GLY-TRP-TYR-GLN-L-AZETIDINE-2-CARBOXYLIC ACID-TYR-ALA-LEU-PRO-LEU-NH2;L-Leucinamide, N-acetyl-L-phenylalanyl-L-α-glutamyl-L-tryptophyl-L-threonyl-L-prolylglycyl-L-tryptophyl-L-tyrosyl-L-glutaminyl-(2S)-2-azetidinecarbonyl-L-tyrosyl-L-alanyl-L-leucyl-L-prolyl-;Ac-FEWTPGWYQ(Aze)YALPL-NH2;AF12198(TFA);AF12198, human type I interleukin receptor antagonist
30 prices
Selected condition:
Brand
- aablocks
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth
- ChemScene
- DC Chemicals
- Medical Isotopes, Inc.
- Tocris
- TRC
- Usbiological
Package
- 50ug
- 100ug
- 250ug
- 500ug
- 0.5mg
- 1
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- Manufactureraablocks
- Product numberAA00ACEF
- Product descriptionAF 12198 ≥98%
- Packaging1mg
- Price$239
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ACEF
- Product descriptionAF 12198 ≥98%
- Packaging5mg
- Price$636
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ACEF
- Product descriptionAF 12198 ≥98%
- Packaging10mg
- Price$1060
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ACEF
- Product descriptionAF 12198 ≥98%
- Packaging25mg
- Price$1695
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ACEF
- Product descriptionAF 12198 ≥98%
- Packaging50mg
- Price$2384
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product number2681CW
- Product description(4S)-4-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-5-[[(2S)-1-[[(2S,3R)-1-[(2S)-2-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoyl]azetidin-1-yl]-1,5-dioxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoicacid
- Packaging1mg
- Price$1737
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPEP0004562
- Product descriptionAF12198 95.00%
- Packaging1MG
- Price$830.74
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5175
- Product descriptionAF 12198
- Packaging1mg
- Price$110
- Updated2026-05-06
- Buy
- ManufacturerBiosynth
- Product numberFA109195
- Product descriptionAc-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2
- Packaging50ug
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFA109195
- Product descriptionAc-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2
- Packaging100ug
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberCRB1001289
- Product descriptionAF12198
- Packaging0.5mg
- Price$331.46
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFA109195
- Product descriptionAc-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2
- Packaging1mg
- Price$900
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFA109195
- Product descriptionAc-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2
- Packaging2mg
- Price$900
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFA109195
- Product descriptionAc-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2
- Packaging5mg
- Price$900
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberCRB1001289
- Product descriptionAF12198
- Packaging5mg
- Price$959.45
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberCRB1001289
- Product descriptionAF12198
- Packaging1mg
- Price$453.57
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00ACEF | AF 12198 ≥98% | 1mg | $239 | 2026-05-28 | Buy |
| aablocks | AA00ACEF | AF 12198 ≥98% | 5mg | $636 | 2026-05-28 | Buy |
| aablocks | AA00ACEF | AF 12198 ≥98% | 10mg | $1060 | 2026-05-28 | Buy |
| aablocks | AA00ACEF | AF 12198 ≥98% | 25mg | $1695 | 2026-05-28 | Buy |
| aablocks | AA00ACEF | AF 12198 ≥98% | 50mg | $2384 | 2026-05-28 | Buy |
| AK Scientific | 2681CW | (4S)-4-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-5-[[(2S)-1-[[(2S,3R)-1-[(2S)-2-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoyl]azetidin-1-yl]-1,5-dioxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoicacid | 1mg | $1737 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0004562 | AF12198 95.00% | 1MG | $830.74 | 2021-12-16 | Buy |
| ApexBio Technology | B5175 | AF 12198 | 1mg | $110 | 2026-05-06 | Buy |
| Biosynth | FA109195 | Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2 | 50ug | $200 | 2021-12-16 | Buy |
| Biosynth | FA109195 | Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2 | 100ug | $300 | 2021-12-16 | Buy |
| Biosynth | CRB1001289 | AF12198 | 0.5mg | $331.46 | 2026-06-04 | Buy |
| Biosynth | FA109195 | Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2 | 1mg | $900 | 2026-06-04 | Buy |
| Biosynth | FA109195 | Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2 | 2mg | $900 | 2026-06-04 | Buy |
| Biosynth | FA109195 | Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2 | 5mg | $900 | 2026-06-04 | Buy |
| Biosynth | CRB1001289 | AF12198 | 5mg | $959.45 | 2026-06-04 | Buy |
| Biosynth | CRB1001289 | AF12198 | 1mg | $453.57 | 2026-06-04 | Buy |
Properties
Melting point :>179°C (dec.)
Density :1.353±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO (Slightly), Methanol (Slightly), Water (Very Slightly)
form :solid
pka :4.44±0.10(Predicted)
color :White to Off-White
Sequence :Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-{Aze}-Tyr-Ala-Leu-Pro-Leu-NH2
Density :1.353±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO (Slightly), Methanol (Slightly), Water (Very Slightly)
form :solid
pka :4.44±0.10(Predicted)
color :White to Off-White
Sequence :Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-{Aze}-Tyr-Ala-Leu-Pro-Leu-NH2
Safety Information
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Description
AF 12198 is a peptide that selectively binds Interleukin-1 (IL-1) receptor and blocks in vivo responses to IL-1 (1). The interleukin-1 receptor can activate the innate immune response by binding to cytokines (2). Dysregulation of cytokine production can lead to aberrant immune cells activation that could result in auto-inflammatory disorders.More related product prices
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AF12198
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