BI-6C9
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- $55 - $2455.5
- Product name: BI-6C9
- CAS: 791835-21-7
- MF: C23H25N3O4S2
- MW: 471.59
- EINECS:
- MDL Number:MFCD07784498
- Synonyms:N-[4-(4-aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide;Butanamide, N-[4-[(4-aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-;N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide;Inhibitor,fission,Neurodegeneration,Bid,BI6C9,BI 6C9,Mitochodondrial,death,Mitochondria,Apoptosis,inhibit,Glutamate,stress,Neuronal,Bcl-2,Mitochondrial,Mitochondrial Metabolism,potential,cell,Oxidative,membrane,BI-6C9,BI-6C-9;BI-6C9, 10 mM in DMSO
36 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Biosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- TRC
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- Manufactureraablocks
- Product numberAA005340
- Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97
- Packaging25mg
- Price$337
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005340
- Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97
- Packaging50mg
- Price$490
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005340
- Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97
- Packaging100mg
- Price$679
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005340
- Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97
- Packaging200mg
- Price$892
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005340
- Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97
- Packaging10mg
- Price$198
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005340
- Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97
- Packaging5mg
- Price$138
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005340
- Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97
- Packaging2mg
- Price$90
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005340
- Product descriptionN-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97%
- Packaging1mg
- Price$59
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY230417
- Product descriptionBI-6C9 98%
- Packaging100MG
- Price$945
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY230417
- Product descriptionBI-6C9 98%
- Packaging25MG
- Price$505
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY230417
- Product descriptionBI-6C9 98%
- Packaging5MG
- Price$170
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number8956CS
- Product descriptionN-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide
- Packaging1mg
- Price$159
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8956CS
- Product descriptionN-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide
- Packaging5mg
- Price$367
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1173077
- Product descriptionBI-6C9 97%
- Packaging10mg
- Price$274
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA1173077
- Product descriptionBI-6C9 97%
- Packaging5mg
- Price$178
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA1173077
- Product descriptionBI-6C9 97%
- Packaging1mg
- Price$74
- Updated2026-06-05
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA005340 | N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97 | 25mg | $337 | 2026-05-28 | Buy |
| aablocks | AA005340 | N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97 | 50mg | $490 | 2026-05-28 | Buy |
| aablocks | AA005340 | N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97 | 100mg | $679 | 2026-05-28 | Buy |
| aablocks | AA005340 | N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97 | 200mg | $892 | 2026-05-28 | Buy |
| aablocks | AA005340 | N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97 | 10mg | $198 | 2026-05-28 | Buy |
| aablocks | AA005340 | N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97 | 5mg | $138 | 2026-05-28 | Buy |
| aablocks | AA005340 | N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97 | 2mg | $90 | 2026-05-28 | Buy |
| aablocks | AA005340 | N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide 97% | 1mg | $59 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y230417 | BI-6C9 98% | 100MG | $945 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y230417 | BI-6C9 98% | 25MG | $505 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y230417 | BI-6C9 98% | 5MG | $170 | 2026-05-27 | Buy |
| AK Scientific | 8956CS | N-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide | 1mg | $159 | 2021-12-16 | Buy |
| AK Scientific | 8956CS | N-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide | 5mg | $367 | 2021-12-16 | Buy |
| Ambeed | A1173077 | BI-6C9 97% | 10mg | $274 | 2026-06-05 | Buy |
| Ambeed | A1173077 | BI-6C9 97% | 5mg | $178 | 2026-06-05 | Buy |
| Ambeed | A1173077 | BI-6C9 97% | 1mg | $74 | 2026-06-05 | Buy |
Properties
Density :1.36±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 24 mg/mL, soluble
form :solid
pka :11.58±0.50(Predicted)
color :off-white
InChI :1S/C23H25N3O4S2/c1-30-19-8-14-22(15-9-19)32(28,29)25-16-2-3-23(27)26-18-6-12-21(13-7-18)31-20-10-4-17(24)5-11-20/h4-15,25H,2-3,16,24H2,1H3,(H,26,27)
InChIKey :LCFUJBSKPDPGKO-UHFFFAOYSA-N
SMILES :COc1ccc(cc1)S(=O)(=O)NCCCC(=O)Nc2ccc(Sc3ccc(N)cc3)cc2
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 24 mg/mL, soluble
form :solid
pka :11.58±0.50(Predicted)
color :off-white
InChI :1S/C23H25N3O4S2/c1-30-19-8-14-22(15-9-19)32(28,29)25-16-2-3-23(27)26-18-6-12-21(13-7-18)31-20-10-4-17(24)5-11-20/h4-15,25H,2-3,16,24H2,1H3,(H,26,27)
InChIKey :LCFUJBSKPDPGKO-UHFFFAOYSA-N
SMILES :COc1ccc(cc1)S(=O)(=O)NCCCC(=O)Nc2ccc(Sc3ccc(N)cc3)cc2
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
BH3-interacting domain (Bid) is cleaved by caspase-8 to produce the truncated protein tBid, which facilitates cytochrome c release from mitochondria and drives apoptosis. BI-6C9 is an inhibitor of tBid (Kd = 20 μM), blocking the release of both cytochrome c and second mitochondria-derived activator of caspase from mitochondria. It prevents apoptosis in neurons treated with glutamate or oxygen-glucose deprivation. BI-6C9 (10 μM) also inhibits the nuclear translocation of apoptosis-inducing factor AIF, preventing the death of ovarian OVCAR-3 cancer cells induced by IFN-α2a.More related product prices
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