DEMECOLCINE
|
- $30 - $16040
- Product name: DEMECOLCINE
- CAS: 477-30-5
- MF: C21H25NO5
- MW: 371.43
- EINECS:207-514-6
- MDL Number:MFCD00075459
- Synonyms:substancef ;Colcemide;DEMECOLCINE HYBRI-MAXR;DEMECOLCINE SOLUTION 10 UG/ML;Colcemid-D3=Demecolcine-D3;N-Deacetyl-N-methyl(deutero)colchicine;COLCEMID;COLCEMIDE(R)
55 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AHH
- AK Scientific
- Alichem
- American Custom Chemicals Corporation
- Arctom
- Cayman Chemical
- DC Chemicals
- Labseeker
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Thermo Scientific Chemicals
- TRC
- Usbiological
Package
- 20mg
- 5g
- 20ml
- 100ml
- 1 unit
- 1 g
- 10 mg
- 500 mg
- 10mM*1mLinDMSO(Solution)
- 1mg
- 5mg
- 10mg
- 25mg
- 0.05g
- 50mg
- 100MG
- 10mM*1mLinDMSO(Solid+Solvent)
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3567-M001
- Product descriptionColcemid ≥98%(HPLC)
- Packaging1mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3567-M001
- Product descriptionColcemid ≥98%(HPLC)
- Packaging1mg
- Price$30
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3567-M005
- Product descriptionColcemid ≥98%(HPLC)
- Packaging5mg
- Price$75
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-C0022-M025
- Product descriptionColcemid ≥98%(HPLC)
- Packaging25mg
- Price$290
- Updated2026-05-06
- Buy
- ManufacturerAHH
- Product numberMT-49841
- Product descriptionDemecolcine 97%
- Packaging0.05g
- Price$290
- Updated2026-05-25
- Buy
- ManufacturerAHH
- Product numberMT-49841
- Product descriptionDemecolcine 97%
- Packaging0.05g
- Price$290
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberV0182
- Product descriptionDemecolcine
- Packaging5mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberV0182
- Product descriptionDemecolcine
- Packaging10mg
- Price$276
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberV0182
- Product descriptionDemecolcine
- Packaging1mg
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number477305
- Product description(S)-1,2,3,10-Tetramethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one
- Packaging10mg
- Price$325.71
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number477305
- Product description(S)-1,2,3,10-Tetramethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one
- Packaging50mg
- Price$1016.61
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002097
- Product descriptionColcemid 95.00%
- Packaging100MG
- Price$1732.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002097
- Product descriptionColcemid 95.00%
- Packaging10MG
- Price$721.88
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002097
- Product descriptionColcemid 95.00%
- Packaging1MG
- Price$135.45
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-N0282R
- Product descriptionColcemid (Standard) 99.84%
- Packaging1mg
- Price$134
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N0282
- Product descriptionDemecolcine 99.81%
- Packaging5mg
- Price$114
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3567-M001 | Colcemid ≥98%(HPLC) | 1mg | $30 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-3567-M001 | Colcemid ≥98%(HPLC) | 1mg | $30 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3567-M005 | Colcemid ≥98%(HPLC) | 5mg | $75 | 2026-05-06 | Buy |
| Adipogen Life Sciences | CDX-C0022-M025 | Colcemid ≥98%(HPLC) | 25mg | $290 | 2026-05-06 | Buy |
| AHH | MT-49841 | Demecolcine 97% | 0.05g | $290 | 2026-05-25 | Buy |
| AHH | MT-49841 | Demecolcine 97% | 0.05g | $290 | 2026-05-26 | Buy |
| AK Scientific | V0182 | Demecolcine | 5mg | $198 | 2021-12-16 | Buy |
| AK Scientific | V0182 | Demecolcine | 10mg | $276 | 2021-12-16 | Buy |
| AK Scientific | V0182 | Demecolcine | 1mg | $139 | 2021-12-16 | Buy |
| Alichem | 477305 | (S)-1,2,3,10-Tetramethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one | 10mg | $325.71 | 2021-12-16 | Buy |
| Alichem | 477305 | (S)-1,2,3,10-Tetramethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-9(5H)-one | 50mg | $1016.61 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002097 | Colcemid 95.00% | 100MG | $1732.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002097 | Colcemid 95.00% | 10MG | $721.88 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002097 | Colcemid 95.00% | 1MG | $135.45 | 2021-12-16 | Buy |
| Arctom | HY-N0282R | Colcemid (Standard) 99.84% | 1mg | $134 | 2026-05-26 | Buy |
| Arctom | HY-N0282 | Demecolcine 99.81% | 5mg | $114 | 2026-05-26 | Buy |
Properties
Melting point :73-75°C
alpha :D20 -129.0° (c = 1 in chloroform)
Boiling point :501.11°C (rough estimate)
Density :1.2350 (rough estimate)
refractive index :1.5614 (estimate)
storage temp. :2-8°C
solubility :DMSO: 10 mg/mL
form :powder
pka :8.48±0.40(Predicted)
color :White to off-white
Sensitive :Air & Light Sensitive
BRN :2822892
Stability :Hygroscopic
InChI :1S/C21H25NO5/c1-22-15-8-6-12-10-18(25-3)20(26-4)21(27-5)19(12)13-7-9-17(24-2)16(23)11-14(13)15/h7,9-11,15,22H,6,8H2,1-5H3
InChIKey :NNJPGOLRFBJNIW-UHFFFAOYSA-N
SMILES :N(C1CCc2c(c(c(c(c2)OC)OC)OC)C3=CC=C(C(=O)C=C31)OC)C
alpha :D20 -129.0° (c = 1 in chloroform)
Boiling point :501.11°C (rough estimate)
Density :1.2350 (rough estimate)
refractive index :1.5614 (estimate)
storage temp. :2-8°C
solubility :DMSO: 10 mg/mL
form :powder
pka :8.48±0.40(Predicted)
color :White to off-white
Sensitive :Air & Light Sensitive
BRN :2822892
Stability :Hygroscopic
InChI :1S/C21H25NO5/c1-22-15-8-6-12-10-18(25-3)20(26-4)21(27-5)19(12)13-7-9-17(24-2)16(23)11-14(13)15/h7,9-11,15,22H,6,8H2,1-5H3
InChIKey :NNJPGOLRFBJNIW-UHFFFAOYSA-N
SMILES :N(C1CCc2c(c(c(c(c2)OC)OC)OC)C3=CC=C(C(=O)C=C31)OC)C
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Colcemid is a colchicine derivative that inhibits tubulin polymerization as potently as colchicine (IC50 = 2.1 and 2.4 μM, respectively) but is less toxic. At very low (nanomolar) concentrations, colcemid suppresses microtubule dynamicity and inhibits cell migration, while at micromolar levels it blocks microtubule assembly, arresting cells in metaphase. Mitotic block by colcemid is used to synchronize cells and for karyotyping in cytogenetic studies. Prolonged exposure to colcemid can activate p53, leading to apoptosis.More related product prices
ColchicineRelated product price
- COLCHICOSIDE
$36-490 - DEMECOLCINE
$30-16040 - GLORIOSINE
$65-855
Suppliers and manufacturers
ANHUI WITOP BIOTECH CO., LTD
Dayang Chem (Hangzhou) Co.,Ltd.
GIHI CHEMICALS CO.,LIMITED
Shanghai Acmec Biochemical Technology Co., Ltd.
SHANGHAI KEAN TECHNOLOGY CO., LTD.
ShangHai IKSChem Technology Co.,LTD
