4-Carboxylphenylboronic acid pinacol ester synthesis
- Product Name:4-Carboxylphenylboronic acid pinacol ester
- CAS Number:180516-87-4
- Molecular formula:C13H17BO4
- Molecular Weight:248.08
76-09-5
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$8.20/250mg
14047-29-1
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$10.00/5 g
180516-87-4
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$8.00/1g
Yield:180516-87-4 93.7%
Reaction Conditions:
in hexane at 70; for 3 h;Temperature;Time;Concentration;
Steps:
1
To a 500 mL reaction flask was added p-carboxyphenylboronic acid (50 g, 0.3 mol), pinacol (39 g, 0.33 mol), n-hexane 100 g, and the temperature was raised to 70 ° C, and the reaction was carried out for 3 hours, and concentrated under reduced pressure. Drying in vacuo gave 73 g of 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid as a white solid. Yield: 98%.
References:
Zhejiang Keju Bio-pharmaceutical Co., Ltd.;Yang Yong;Yang Ming;Shen Chao;Wang Dong CN109053780, 2018, A Location in patent:Paragraph 0021; 0038; 0041; 0047; 0053; 0059; 0065; 0071
150-13-0
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73183-34-3
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180516-87-4
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$8.00/1g
619-58-9
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25015-63-8
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$22.40/5G
180516-87-4
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586-76-5
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73183-34-3
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$6.00/5g
180516-87-4
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$8.00/1g
124-38-9
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195062-61-4
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180516-87-4
247 suppliers
$8.00/1g