| Identification | Back Directory | [Name]
Propargyl-PEG8-alcohol | [CAS]
1422023-54-8 | [Synonyms]
Alkyne-PEG7-OH
Propargyl-PEG7-OH
Propargyl-PEG8-alcohol
3,6,9,12,15,18,21-Heptaoxatetracos-23-yn-1-ol | [Molecular Formula]
C17H32O8 | [MDL Number]
MFCD28950752 | [MOL File]
1422023-54-8.mol | [Molecular Weight]
364.43 |
| Hazard Information | Back Directory | [Description]
Propargyl-PEG8-alcohol has a hydroxyl group and a propargyl group. The propargyl group can participate in copper catalyzed azide-alkyne Click Chemistry. | [Uses]
Propargyl-PEG7-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG7-alcohol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] Goswami LN, et al. Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery. Org Biomol Chem. 2013 Feb 21;11(7):1116-26. DOI:10.1039/c2ob26968f |
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