| Identification | Back Directory | [Name]
Ald-Ph-PEG2-t-butyl ester | [CAS]
1807521-09-0 | [Synonyms]
Ald-Ph-PEG2-COOtBu
CHO-Ph-PEG2-COOtBu
DF-PEG2-CH2CH2COOtBu
CHO-Ph-CONH-PEG2-COOtBu
ALD-PH-PEG2-CH2CH2COOTBU
Ald-Ph-amido-PEG2-C2-Boc
Ald-Ph-PEG2-t-butyl ester
Propanoic acid, 3-[2-[2-[(4-formylbenzoyl)amino]ethoxy]ethoxy]-, 1,1-dimethylethyl ester | [Molecular Formula]
C19 H27 N O6 | [MDL Number]
MFCD28122945 | [MOL File]
1807521-09-0.mol | [Molecular Weight]
365.42 |
| Chemical Properties | Back Directory | [Boiling point ]
547.6±45.0 °C(Predicted) | [density ]
1.132±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C, stored under nitrogen | [solubility ]
Soluble in DMSO, DCM, DMF | [form ]
Viscous Liquid | [pka]
13.53±0.46(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
Ald-Ph-PEG2-t-butyl ester is reactive with aminooxy containing molecules The t-butyl ester can be removed under acidic conditions. | [Uses]
Ald-Ph-amido-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
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