Prazosin Hcl
- CAS No.
- 19237-84-4
- Chemical Name:
- Prazosin Hcl
- Synonyms
- PRAZOSIN HCL;(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(furan-2-yl)methanone hydrochloride;hypovase;pratsiol;sinetens;Vasoflex;peripress;Adversuten;Alpress LP;cp-12299-1
- CBNumber:
- CB00129335
- Molecular Formula:
- C19H22ClN5O4
- Molecular Weight:
- 419.86
- MDL Number:
- MFCD00058177
- MOL File:
- 19237-84-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 277 - 280 °C |
|---|---|
| storage temp. | 2-8°C |
| solubility | H2O: 1 mg/mL, clear, colorless |
| form | solid |
| color | white |
| Water Solubility | Soluble in dimethyl sulfoxide, ethanol, water, methanol. |
| Merck | 14,7717 |
| BRN | 4303561 |
| InChI | InChI=1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22);1H |
| InChIKey | WFXFYZULCQKPIP-UHFFFAOYSA-N |
| SMILES | N1(C2=NC(N)=C3C(=N2)C=C(OC)C(OC)=C3)CCN(C(C2=CC=CO2)=O)CC1.[H]Cl |
| CAS DataBase Reference | 19237-84-4(CAS DataBase Reference) |
| FDA UNII | X0Z7454B90 |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335-H361 | |||||||||
| Precautionary statements | P201-P301+P312+P330-P302+P352-P305+P351+P338-P308+P313 | |||||||||
| target organs | Central nervous system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38-62 | |||||||||
| Safety Statements | 28-36 | |||||||||
| RIDADR | 3249 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VA1350000 | |||||||||
| F | 10 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 2934990002 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Repr. 2 STOT RE 2 STOT SE 3 |
|||||||||
| Hazardous Substances Data | 19237-84-4(Hazardous Substances Data) | |||||||||
| Toxicity | dog,LD50,oral,> 700mg/kg (700mg/kg),GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDSKIDNEY, URETER, AND BLADDER: OTHER CHANGES GASTROINTESTINAL: NAUSEA OR VOMITING,Oyo Yakuri. Pharmacometrics. Vol. 17, Pg. 39, 1979. | |||||||||
| NFPA 704 |
|
Prazosin Hcl price More Price(73)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR3099 | Prazosin Hydrochloride pharmaceutical secondary standard, certified reference material | 19237-84-4 | 500MG | $266 | 2026-04-30 | Buy |
| Sigma-Aldrich | P7791 | Prazosin hydrochloride ≥99.0% (HPLC) | 19237-84-4 | 1g | $1050 | 2026-04-30 | Buy |
| Sigma-Aldrich | P2680000 | Prazosin hydrochloride European Pharmacopoeia (EP) Reference Standard | 19237-84-4 | 30 mg | $175 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1554705 | Prazosin hydrochloride United States Pharmacopeia (USP) Reference Standard | 19237-84-4 | 350mg | $435 | 2026-04-30 | Buy |
| TCI Chemical | P0938 | Prazosin Hydrochloride >98.0%(T) | 19237-84-4 | 100mg | $63 | 2026-04-30 | Buy |
Prazosin Hcl Chemical Properties,Uses,Production
Description
Prazosin Hcl, a quinazoline derivative, is the first of a new chemical class of antihypertensives.
Physical properties
Prazosin Hcl is a white, crystalline substance, slightly soluble in water and isotonic saline, and has a molecular weight of 419.87.
Uses
Prazosin Hcl is indicated for the treatment of hypertension, to lower blood pressure. It can be used alone or in combination with other antihypertensive drugs such as diuretics or beta-adrenergic blocking agents.
Brand name
Minipress (Pfizer)
Biological Activity
α 1 and α 2B -adrenoceptor antagonist. Also a potent antagonist at the melatonin MT 3 receptor (K i = 10.2 nM). Also available as part of the α 1 -Adrenoceptor Tocriset™ and Mixed Adrenergic Tocriset™ .
Biochem/physiol Actions
Peripheral α1-adrenoceptor antagonist; vasodilator. Prazosin Hcl can be used to treat chronic posttraumatic stress disorder (PTSD). It plays a role in reducing blood pressure by relaxing blood vessels, hence used in the treatment of high blood pressure.
Side effects
Headache, drowsiness, tiredness, weakness, blurred vision, nausea, vomiting, diarrhea, or constipation
Prazosin Hcl Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Ascent Scientific | 4401179829988 | customerservice@ascentscientific.co.uk | United Kingdom | 279 | 60 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
View Lastest Price from Prazosin Hcl manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2024-03-15 | Prazosin
19216-56-9
|
$25.00-35.00 | 1kg | 99.8% | 200tons/year | Sigma Audley | |
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2021-07-13 | Prazosin
19216-56-9
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
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2020-05-10 | Prazosin
19216-56-9
|
1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd |









