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Ethyl Succinyl Chloride

Ethyl Succinyl Chloride Structure
Ethyl Succinyl Chloride structure
CAS No.
14794-31-1
Chemical Name:
Ethyl Succinyl Chloride
Synonyms
Ethyl 4-chloro-4-oxobutanoate;Ethyl succinoyl chloride;ETHYL 4-CHLORO-4-OXOBUTYRATE;ETHYL 3-(CHLOROFORMYL)PROPIONATE;Butanoic acid, 4-chloro-4-oxo-, ethyl ester;SKL1293;oro-4-oxobutyrate;ETHYL SUCCINYL CHLORIDE;Ethyl siccinyl chloride;ETHYLSS-BENZOYLACRYLATE
CBNumber:
CB0107033
Molecular Formula:
C6H9ClO3
Molecular Weight:
164.59
MDL Number:
MFCD00000751
MOL File:
14794-31-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 17:22:14
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Ethyl Succinyl Chloride Properties

Boiling point 88-90 °C11 mm Hg(lit.)
Density 1.155 g/mL at 25 °C(lit.)
vapor pressure 48.2Pa at 25℃
refractive index n20/D 1.437(lit.)
Flash point 184 °F
storage temp. 2-8°C
solubility soluble in Chloroform, Ethyl Acetate
form Liquid
Specific Gravity 1.144 to 1.17
color Clear colorless to yellow
Water Solubility 59.01g/L at 25℃
Sensitive Moisture Sensitive
BRN 1766126
InChI 1S/C6H9ClO3/c1-2-10-6(9)4-3-5(7)8/h2-4H2,1H3
InChIKey IXZFDJXHLQQSGQ-UHFFFAOYSA-N
SMILES CCOC(=O)CCC(Cl)=O
LogP 0.05
CAS DataBase Reference 14794-31-1(CAS DataBase Reference)
FDA UNII CFH5LG292R
NIST Chemistry Reference Butanoic acid, 4-chloro-4-oxo-, ethyl ester(14794-31-1)
EPA Substance Registry System Butanoic acid, 4-chloro-4-oxo-, ethyl ester (14794-31-1)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C
Risk Statements  34-36/37-14
Safety Statements  26-27-36/37/39-45-24/25
RIDADR  UN 3265 8/PG 2
WGK Germany  3
TSCA  TSCA listed
HazardClass  8
PackingGroup  II
HS Code  29171990
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Skin Corr. 1B
REACH Registrations Active
Limited Quantities 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
2
3 0

Ethyl Succinyl Chloride price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 190705 Ethyl 4-chloro-4-oxobutyrate 95% 14794-31-1 25g $72.6 2026-04-30 Buy
Sigma-Aldrich 190705 Ethyl 4-chloro-4-oxobutyrate 95% 14794-31-1 100g $190 2026-04-30 Buy
TCI Chemical E0368 Ethyl Succinyl Chloride >95.0%(T) 14794-31-1 25g $90 2026-04-30 Buy
TCI Chemical E0368 Ethyl Succinyl Chloride >95.0%(T) 14794-31-1 500g $460 2026-04-30 Buy
Usbiological 275518 Ethyl 4-chloro-4-oxobutyrate Asreported 14794-31-1 500g $326 2026-06-03 Buy
Product number Packaging Price Buy
190705 25g $72.6 Buy
190705 100g $190 Buy
E0368 25g $90 Buy
E0368 500g $460 Buy
275518 500g $326 Buy

Ethyl Succinyl Chloride Chemical Properties,Uses,Production

Chemical Properties

clear colourless to yellow liquid

Uses

Ethyl 4-chloro-4-oxobutyrate was used in the synthesis of:

  • polymer-supported bifunctional catalyst
  • succinimidyl ester of benzo(a)pyrene
  • succinate prodrugs of curcuminoids

Flammability and Explosibility

Not classified

Synthesis

MONO-ETHYL SUCCINATE

1070-34-4

Ethyl Succinyl Chloride

14794-31-1

The general procedure for the synthesis of monoethyl succinate chloride from monoethyl succinate: monoethyl succinate (116.8 g, 0.8 mol), dichloromethane (300 mL) and thionyl chloride (104 g, 0.88 mol) were added to a reaction flask, N,N-dimethylformamide (0.8 g) was added under nitrogen protection, and heated and stirred by refluxing for 5 hours at 38°C. The reaction was completed with a solution of dichloromethane (124 g, 0.88 mol). Upon completion of the reaction, a dichloromethane solution of monoethylsuccinic acid chloride (124 g, yield: 95%) was obtained.

References

[1] Heterocycles, 2001, vol. 55, # 8, p. 1487 - 1498
[2] Journal of Medicinal Chemistry, 2007, vol. 50, # 7, p. 1528 - 1536
[3] Patent: CN104326922, 2016, B. Location in patent: Paragraph 0038; 0040
[4] Journal of the American Chemical Society, 1991, vol. 113, # 6, p. 2071 - 2092
[5] Journal of Organic Chemistry, 1996, vol. 61, # 14, p. 4848 - 4852

Ethyl Succinyl Chloride synthesis

1070-34-4
14794-31-1
Synthesis of Ethyl Succinyl Chloride from Mono-ethyl succinate

Ethyl Succinyl Chloride Preparation Products And Raw materials

Raw materials

Succinic anhydride Monoethyl fumarate Mono-ethyl succinate Ethanol Thionyl chloride
Diethyl succinate N,N-Dimethylformamide Dichloromethane

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Preparation Products

5-hydroxy-4-oxopentanoic acid 2-[(4-Ethoxy-1,4-dioxobutyl)amino]benzoic acid ethyl ester Ethyl 4-[3,4-(ethylenedioxy)phenyl]-4-oxobutyrate Ethyl 4-(2-thiazolyl)-4-oxobutyrate Ethyl 4-(4-methoxy-3-methylphenyl)-4-oxobutanoate
Ethyl 4-(2,4-dimethoxyphenyl)-4-oxobutyrate Ethyl 4-(3,5-dimethoxyphenyl)-4-oxobutyrate Ethyl 4-oxo-4-(3-thienyl)butyrate 4-Oxooctanoic acid ethyl ester

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Ethyl Succinyl Chloride Suppliers

Global( 373)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TAIYUAN RHF CO.,LTD. 56
TCI (Shanghai) Development Co., Ltd. 81
ShangHai DEMO Chemical Co.,Ltd 57
Energy Chemical 61
Beijing Ouhe Technology Co., Ltd 60
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Pure Chemistry Scientific Inc. 62

View Lastest Price from Ethyl Succinyl Chloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ethyl Succinyl Chloride pictures 2026-06-30 Ethyl Succinyl Chloride
14794-31-1
 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
Ethyl Succinyl Chloride pictures 2026-05-28 Ethyl Succinyl Chloride
14794-31-1
 $2.00-5.00 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
Ethyl Succinyl Chloride pictures 2025-06-27 Ethyl Succinyl Chloride
14794-31-1
 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd

Ethyl Succinyl Chloride Spectrum

Ethyl Succinyl Chloride(14794-31-1)1HNMREthyl Succinyl Chloride(14794-31-1)RamanEthyl Succinyl Chloride(14794-31-1)IREthyl Succinyl Chloride(14794-31-1)FT-IR

14794-31-1(Ethyl Succinyl Chloride)Related Search:

Butyryl chloride Diisopropyl succinate 4-Chlorobutyl methyl ether Butyric Acid Sodium propionate
SUCCINALDEHYDE Methyl 4-chlorobutyrate 1-Chlorobutane Methyl 4-chloro-4-oxobutanoate 1-Butanol
Methyl 4-oxobutanoate Methyl butyrate Butyl ethyl ether Ethyl Succinyl Chloride 1-Propanol
4-Chlorobutyric acid Ethyl 4-chlorobutyrate Succinaldehydic acid

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BETA CARBETHOXY PROPIONYL CHLORIDE ETHYL SUCCINYL CHLORIDE ETHYL 4-CHLORO-4-OXOBUTYRATE Ethyl siccinyl chloride ETHYL 4-CHLORO-4-OXOBUTYRATE,95% Ethyl succinyl chloride, tech., 95% 3-CARBETHOXYPROPIONYL CHLORIDE (Ethyl Succinyl Chloride) 3-Carbethoxypropionyl chloride 3-Ethoxycarbonylpropionyl chloride SUCCINIC ACID MONOETHYL ESTER CHLORIDE 3-Carboethoxypropionyl chloride 4-chloro-4-oxo-butanoicaciethylester beta-Ethoxycarbonylpropionyl chloride Ethyl succinoyl chloride Propionic acid, 3-(chloroformyl)-, ethyl ester 2-ethylbutanedioyl dichloride Monoethyl succinyl chloride Butanoic acid, 4-chloro-4-oxo-, ethyl ester 4-chloro-4-oxo-butanoic acid ethyl ester -Carbethoxy propionyl chloride 3-(Ethoxycarbonyl)propanoyl chloride (Succinic acid 1-ethyl) chloride 3-(Chloroformyl)propionic acid ethyl ester 4-Chloro-4-oxobutyric acid ethyl ester 4-Oxo-4-chlorobutanoic acid ethyl ester 4-Oxo-4-chlorobutyric acid ethyl ester ETHYLSS-BENZOYLACRYLATE Ethyl succinyl chloride,98% Ethyl 4-chloro-4-oxobutyrate, 95.0%(T) Ethyl succinyl chloride(ESC) Ethyl 4-chloro-4-oxobutyrate 95% Ethyl succinyl chloride, 95&percnt: Succinic acid ethyl ester chloride EthylSuccinylChloride> oro-4-oxobutyrate SKL1293 TIANFU-CHEM Ethyl 3-(chloroformyl)propionate 14794-31-1 ETHYL SUCCINYL CHLORIDE Extra Pure Monoethyl succinate chloride ETHYL 3-(CHLOROFORMYL)PROPIONATE Ethyl 4-chloro-4-oxobutanoate 14794-31-1 14794-31-3 ClCOCH2CH2CO2C2H5 ClOCCH2CH2CO2CH2CH3 C6H9ClO3 Carbonyl Compounds Building Blocks ACID CHLORIDE Acid Halides Organic Building Blocks bc0001