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4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride

4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Structure
4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride structure
CAS No.
106261-64-7
Chemical Name:
4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride
Synonyms
Imatinib Impurity 48;Imatinib Intermediate 5;4-(4-Methylpiperizinomethyl)benzoylchloride2HCl;4-[(4-Methyl-1-piperazinyl)Methyl]benzoyl chloride;4-(4-Methylpiperazinylmethyl)benzoyl chloride DiHCl;4-(4-Methyl-1-Piperazinyl) Methyl Benzoyl Chloride 2HCl;4-(4-Methyl-1-Piperazinyl) Methyl Benzoyl Chloride 2HCI;4-(4-Methylpiperizinomethyl)benzoylchloridedihydrochloride;4-(4-methylpiperazin-1-yl）benzoyl chloride dihydrochloride;4-(4-METHYLPIPERAZINYLMETHYL)BENZOYL CHLORIDE DIHYDROCHLORIDE
CBNumber:
CB01073537
Molecular Formula:
C13H18Cl2N2O
Molecular Weight:
289.2
MDL Number:
MFCD11519983
MOL File:
106261-64-7.mol
MSDS File:
SDS
Last updated:2026-05-27 17:05:12
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4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Properties

Melting point >240°C (dec.)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly)
form Solid
color White to Off-White
Water Solubility 100vol% at 20℃[vol%]
Stability Hygroscopic, Moisture Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P305+P351+P338-P310
REACH Registrations Active

4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-M880535-5G 4-((4-Methylpiperazin-1-yl)methyl)benzoyl Chloride Dihydrochloride 5g $834 2026-06-03 Buy
Matrix Scientific 130570 4-(4-Methylpiperazinylmethyl)benzoyl-chloride dihydrochloride 106261-64-7 1.00g $489 2026-05-18 Buy
aablocks AA008U6T 4-((4-Methylpiperazin-1-yl)methyl)benzoyl chloride dihydrochloride 97% 106261-64-7 1g $29 2026-05-28 Buy
aablocks AA008U6T 4-((4-Methylpiperazin-1-yl)methyl)benzoyl chloride dihydrochloride 97% 106261-64-7 5g $78 2026-05-28 Buy
aablocks AA008U6T 4-((4-Methylpiperazin-1-yl)methyl)benzoyl chloride dihydrochloride 97% 106261-64-7 25g $238 2026-05-28 Buy
Product number Packaging Price Buy
TRC-M880535-5G 5g $834 Buy
130570 1.00g $489 Buy
AA008U6T 1g $29 Buy
AA008U6T 5g $78 Buy
AA008U6T 25g $238 Buy

4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Chemical Properties,Uses,Production

Uses

4-((4-Methylpiperazin-1-yl)methyl)benzoyl Chloride Dihydrochloride is an intermediate in the synthesis of Gleevec N-4-((4-Methylpiperazin-1-yl)methyl)benzaldehyde (G407010), an impurity of Gleevec (G407000), a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).

Synthesis

Imaric acid 1g (5g, 0.021 mol, Anegi chemical) into 100mL three-necked bottle, add dichlorosulfoxide (35mL) and catalyst N, N-dimethylformamide (0.3mL), heating reflux reaction for 22 hours, reduced to room temperature, pumping and filtration, n-hexane washing (10mL 2), 45 ~ 50 C drying in vacuum for 2 hours, to obtain a white solid state of 4-(4- 4-(4-methylpiperazinylmethyl)benzoyl chloride dihydrochloride (1h) 5.1g, yield 95%.

4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Suppliers

Global( 100)Suppliers
Supplier Tel Email Country ProdList Advantage
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Shanghai Licheng Chemicals Co., Ltd. +86 (21) 5756-1621 export@shlcchem.com China 62 60
Changzhou DongChen Pharmaceutical Co., Ltd. 0519-88995800 13815038136;13815038136 gjf@dcpharmtech.com China 62 55
Hubei XinyuanShun Chemical Co., Ltd. 13971561712, 13995564702, 027-50664929 hbeixys2001@163.com China 3110 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai YuLue Chemical Co., Ltd. 021-60345187 13671753212 lzz841106@aliyun.com China 10244 55
Nanjing Chalf-Pharm Technology Co., Ltd. 025-57018978 18251899859 sales@chalf-pharm.com China 5855 50
Shanghai QianYan Bio-technology Co., Ltd 02781293128 orders@biochemsafebuy.com China 9904 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Supplier Advantage
Jia Xing Isenchem Co.,Ltd 66
Shanghai T&W Pharmaceutical Co., Ltd. 58
Shanghai Licheng Chemicals Co., Ltd. 60
Changzhou DongChen Pharmaceutical Co., Ltd. 55
Hubei XinyuanShun Chemical Co., Ltd. 55
Bide Pharmatech Ltd. 60
Shanghai YuLue Chemical Co., Ltd. 55
Nanjing Chalf-Pharm Technology Co., Ltd. 50
Shanghai QianYan Bio-technology Co., Ltd 55
Amadis Chemical Company Limited 58

View Lastest Price from 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride pictures 2026-06-30 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride
106261-64-7
 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride pictures 2019-07-06 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride
106261-64-7
 $1.00 1kg 95%-99% 100kg Career Henan Chemical Co
4-(4-Methylpiperazinylmethyl)benzoylchloridedihydrochloride pictures 2018-03-09 4-(4-Methylpiperazinylmethyl)benzoylchloridedihydrochloride
106261-64-7
 99% 100t Shanghai Yingrui Biopharma Co., Ltd.

106261-64-7(4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride)Related Search:

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1of4

4-(4-Methylpiperizinomethyl)benzoylchloride2HCl 4-(4-Methylpiperizinomethyl)benzoylchloridedihydrochloride 4-(4-METHYLPIPERAZINYLMETHYL)BENZOYL CHLORIDE DIHYDROCHLORIDE 4-[(4-Methyl-1-piperazinyl)methyl]benzoyl chloride dihydrochloride 4-[(4-Methyl-1-piperazinyl)Methyl]benzoyl chloride Benzoyl chloride,4-[(4-Methyl-1-piperazinyl)Methyl]-, hydrochloride (1:2) 4‐[(4‐Methyl‐1‐piperazinyl)‐methyl]‐benzoyl chloride hydrochloride 4-(4-Methylpiperazinylmethyl)benzoyl chloride DiHCl 4-(4-methylpiperazin-1-yl）benzoyl chloride dihydrochloride 4-((4-Methylpiperazin-1-yl)methyl)benzoyl chloride dihydrochloride 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochlorid... 4-(4-Methyl piperazine-1-yl)methyl benzoyl chloride dihydrochloride Imatinib Impurity 48 Imatinib Intermediate 5 4-(4-Methyl-1-Piperazinyl) Methyl Benzoyl Chloride 2HCl 4-(4-Methyl-1-Piperazinyl) Methyl Benzoyl Chloride 2HCI 4- (4-methylpiperazine methyl) benzoyl chloride dihydrochloride (Imoyl chloride) 1-[4-(Chlorocarbonyl)benzyl]-4- methylpiperazinediium dichloride 4-(4-Methylpiperazinomethyl)benzoylchloridedihydrochloride(Imatinibacylchloride) 4-(4-Methylpiperazinylmethyl)benzoylchloridedihydrochloride(Imatinibacylchloride) 106261-64-7 C13H19Cl3N2O