2-Amino-3-chloropyridine
- CAS No.
- 39620-04-7
- Chemical Name:
- 2-Amino-3-chloropyridine
- Synonyms
- 3-CHLOROPYRIDIN-2-AMINE;AURORA 15088;IFLAB-BB F3099-7175;OTAVA-BB BB7110951381;Pyridinamine, 3-chloro;3-Choro-2-pyridinamine;2-AMino-3-chloropyridi;Amino-3-Chloropyridine;3-Chloro-2-pyridinamine;2-AMINO-3-CHLOROPYRIDINE
- CBNumber:
- CB0185482
- Molecular Formula:
- C5H5ClN2
- Molecular Weight:
- 128.56
- MDL Number:
- MFCD03541052
- MOL File:
- 39620-04-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 59-62℃ |
|---|---|
| Boiling point | 207.0±20.0 °C(Predicted) |
| Density | 1.326±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | powder to crystal |
| pka | 4.14±0.36(Predicted) |
| color | White to Orange to Green |
| InChI | InChI=1S/C5H5ClN2/c6-4-2-1-3-8-5(4)7/h1-3H,(H2,7,8) |
| InChIKey | RZJPBQGRCNJYBU-UHFFFAOYSA-N |
| SMILES | C1(N)=NC=CC=C1Cl |
| CAS DataBase Reference | 39620-04-7(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-41-37/38-22-20/21/22 | |||||||||
| Safety Statements | 26-36/37/39-39-36/37-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-Amino-3-chloropyridine price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 734691 | 2-Amino-3-chloropyridine 97% | 39620-04-7 | 1g | $47.1 | 2026-04-30 | Buy |
| TCI Chemical | A2497 | 2-Amino-3-chloropyridine >98.0%(GC)(T) | 39620-04-7 | 1g | $87 | 2026-04-30 | Buy |
| AstaTech | 51602 | 2-AMINO-3-CHLOROPYRIDINE 97% | 39620-04-7 | 5G | $28 | 2026-04-30 | Buy |
| AstaTech | 51602 | 2-AMINO-3-CHLOROPYRIDINE 97% | 39620-04-7 | 25G | $34 | 2026-04-30 | Buy |
| AstaTech | 51602 | 2-AMINO-3-CHLOROPYRIDINE 97% | 39620-04-7 | 100G | $93 | 2026-04-30 | Buy |
2-Amino-3-chloropyridine Chemical Properties,Uses,Production
Application
3-Chloro-2-aminopyridine belongs to the pyridine derivatives and is an intermediate in organic synthesis and pharmaceutical chemistry. Industrially, it can be used as a dyeing agent and in the synthesis of active pharmaceutical ingredients.
Chemical Properties
Light green solid
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 24, p. 1313, 1987 DOI: 10.1002/jhet.5570240516
Synthesis
54231-32-2
39620-04-7
The general procedure for the synthesis of 3-chloro-2-aminopyridine from 3-chloro-2-nitropyridine was as follows: 3-chloro-2-nitropyridine (1.00 g, 6.31 mmol) was dissolved in methanol (10 mL), and stannic(II) chloride (5.98 g, 31.54 mmol) and concentrated hydrochloric acid (2.63 mL, 31.54 mmol) were added sequentially. The reaction mixture was stirred at room temperature overnight. After completion of the reaction, the reaction solution was diluted with ethyl acetate and washed with 1N NaOH solution. Subsequently, the organic phase was washed with saturated NaHCO3 solution and dried with anhydrous Na2SO4. Finally, the organic phase was concentrated under reduced pressure to afford the target product 3-chloro-2-aminopyridine (510.0 mg, 63% yield). The product was characterized by 1H NMR (400 MHz, CD3CN) with chemical shifts of δ 6.80 (m, 1H), 7.60 (d, 1H), 8.12 (d, 1H).
References
[1] Patent: WO2006/44775, 2006, A2. Location in patent: Page/Page column 64
[2] Patent: US2009/22670, 2009, A1. Location in patent: Page/Page column 25
2-Amino-3-chloropyridine Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| ChemFuture PharmaTech (Jiangsu) Ltd | 5108538618 | suger.wang@chemfuture.com | China | 832 | 65 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
View Lastest Price from 2-Amino-3-chloropyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-28 | 2-Amino-3-chloropyridine
39620-04-7
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
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2025-06-25 | 2-Amino-3-chloropyridine
39620-04-7
|
$1.10 | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
![]() |
2021-08-12 | 2-Amino-3-chloropyridine
39620-04-7
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-

- 2-Amino-3-chloropyridine
39620-04-7
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-

- 2-Amino-3-chloropyridine
39620-04-7
- $1.10
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-

- 2-Amino-3-chloropyridine
39620-04-7
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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