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2-Amino-6-chloropyridine

2-Amino-6-chloropyridine Structure
2-Amino-6-chloropyridine structure
CAS No.
45644-21-1
Chemical Name:
2-Amino-6-chloropyridine
Synonyms
6-CHLORO-2-PYRIDINAMINE;2-CHLORO-6-AMINOPYRIDINE;2-Pyridinamine,6-chloro;2-CHIORO-6-AMINOPYRIDINE;6-AMINO-2-CHLOROPYRIDINE;6-Chloropyridine-2-amine;6-Chloro-2-aminopyridine;2-amino-6-chloro-pyridin;2-AMINO-6-CHLOROPYRIDINE;6-Chloro-2-pyridineamine
CBNumber:
CB0138776
Molecular Formula:
C5H5ClN2
Molecular Weight:
128.56
MDL Number:
MFCD00234068
MOL File:
45644-21-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 17:18:40
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2-Amino-6-chloropyridine Properties

Melting point 69-73 °C
Boiling point 255.7±20.0 °C(Predicted)
Density 1.326±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka 2.76±0.24(Predicted)
form Powder or Low Melting Solid
color Orange to light brown
BRN 108669
InChI InChI=1S/C5H5ClN2/c6-4-2-1-3-5(7)8-4/h1-3H,(H2,7,8)
InChIKey OBYJTLDIQBWBHM-UHFFFAOYSA-N
SMILES C1(N)=NC(Cl)=CC=C1
CAS DataBase Reference 45644-21-1(CAS DataBase Reference)
UNSPSC Code 12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H312-H332-H302-H315-H319-H335
Precautionary statements  P280h-P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501-P261-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36/37-36
WGK Germany  3
RTECS  US1813350
Hazard Note  Harmful/Irritant
HazardClass  IRRITANT
HS Code  29333990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

2-Amino-6-chloropyridine price More Price(80)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A2263 2-Amino-6-chloropyridine >98.0%(GC)(T) 45644-21-1 5g $58 2026-04-30 Buy
Usbiological 258316 2-Amino-6-chloropyridine Asreported 45644-21-1 5g $366 2026-06-03 Buy
Usbiological 258316 2-Amino-6-chloropyridine Asreported 45644-21-1 10g $496 2026-06-03 Buy
Usbiological 258316 2-Amino-6-chloropyridine Asreported 45644-21-1 25g $746 2026-06-03 Buy
Usbiological 258316 2-Amino-6-chloropyridine Asreported 45644-21-1 50g $981 2026-06-03 Buy
Product number Packaging Price Buy
A2263 5g $58 Buy
258316 5g $366 Buy
258316 10g $496 Buy
258316 25g $746 Buy
258316 50g $981 Buy

2-Amino-6-chloropyridine Chemical Properties, Uses, Production

Chemical Properties

White to light yellow powder

Uses

2-Amino-6-chloropyridine used in a Ni(II)-catalyzed homo-coupling providing diamino-2,2′-bipyridine.

Uses

Substrate used in a Ni(II)-catalyzed homo-coupling providing diamino-2,2′-bipyridine.

Synthesis

2-Chloro-6-nitropyridine

94166-64-0

2-Amino-6-chloropyridine

45644-21-1

The general procedure for the synthesis of 2-amino-6-chloropyridine from 2-chloro-6-nitropyridine was as follows: the TAPEHA-Pd catalyst (0.015 g) was added to EtOH/water (1:1, 20 mL) solution containing nitroaromatics (1.0 mmol). Upon slow addition of NaBH4 (4.0 mmol), the color of the reaction mixture gradually changed to black within a few minutes, indicating the formation of palladium nanoparticles (TAPEHA-PdNPs). The reaction was stirred continuously for 1.5 h at room temperature and atmospheric pressure. After completion of the reaction, the catalyst was removed by filtration and the reaction solution was extracted with EtOAc (3 × 30 mL). The organic layers were combined, dried with MgSO4 and subsequently concentrated under vacuum.

References

[1] Turkish Journal of Chemistry, 2017, vol. 41, # 5, p. 784 - 792
[2] Catalysis Communications, 2015, vol. 67, p. 64 - 67

2-Amino-6-chloropyridine Preparation Products And Raw materials

Raw materials

2-Nitrosobenzaldehyde 6-Chloropicolinic acid 3-Hydroxyglutaronitrile N-(6-aminopyridin-2-yl)acetamide tert-Butyl (6-Chloropyridin-2-yl)-carbamate
2-Chloro-6-nitropyridine N-(6-Chloro-2-pyridinyl)-acetamide 2-Chloro-6-fluoropyridine 2-Chloropyridine-N-oxide 1-Pyridin-2-yl-ethylamine

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Preparation Products

2,6-Diaminopyridine 2-Thiophenemethylamine 2-Amino-6-ethylpyridine 2-Amino-6-methoxy-3-nitropyridine 2-Amino-6-methoxypyridine
2-Pyridinamine,6-(1-piperazinyl)-(9CI)

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2-Amino-6-chloropyridine Suppliers

Global Suppliers ( 453)
Supplier Tel Email Country ProdList Advantage
Fuxin Kaituo Fine Chemical Technology Co., Ltd 15714082442 3757845877@qq.com China 343 58
Wuhan EnTai Technology Development Co,.Ltd 86-27-82330560 2536851935@qq.com China 346 69
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Supplier Advantage
Fuxin Kaituo Fine Chemical Technology Co., Ltd 58
Wuhan EnTai Technology Development Co,.Ltd 69
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
future industrial shanghai co., ltd 65
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
ShangHai DEMO Chemical Co.,Ltd 57
Energy Chemical 61

View Latest Price from 2-Amino-6-chloropyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-6-chloropyridine pictures 2026-08-20 2-Amino-6-chloropyridine
45644-21-1
 $1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
2-Amino-6-chloropyridine pictures 2021-08-11 2-Amino-6-chloropyridine
45644-21-1
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2-Amino-6-chloropyridine pictures 2021-07-02 2-Amino-6-chloropyridine
45644-21-1
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

2-Amino-6-chloropyridine Spectrum

2-Amino-6-chloropyridine(45644-21-1)1HNMR2-Amino-6-chloropyridine(45644-21-1)FT-IR

45644-21-1 (2-Amino-6-chloropyridine) Related Search:

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2-Pyridinamine,6-chloro 2-amino-6-chloro-pyridin 6-CHLOROPYRIDIN-2-YLAMINE 6-CHLORO-2-PYRIDINAMINE 6-AMINO-2-CHLOROPYRIDINE 2-CHIORO-6-AMINOPYRIDINE 2-AMINO-6-CHLOROPYRIDINE (6-CHLOROPYRIDIN-2-YLAMINE) 2-Pyridinamine,6-chloro-(9CI) 6-Chloro-2-aminopyridine 6-Chloropyridine-2-amine 2-Amino-6-chloropyridine,98% 2-CHLORO-6-AMINOPYRIDINE 2-AMINO-6-CHLOROPYRIDINE 2-Amino-6-chloropyridine > 2-Amino-6-chloropyridine ISO 9001：2015 REACH 6-Chloro-2-pyridineamine 45644-21-1 Heterocyclic Building Blocks Halogenated Heterocycles Pyridines Building Blocks PYRIDINE pyridine derivative Amines Pyridines Building Blocks C5 C5 to C6 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks amine| alkyl chloride Isoquinolines ,Heterocyclic Acids