2-Bromo-3-fluorophenol
- CAS No.
- 443-81-2
- Chemical Name:
- 2-Bromo-3-fluorophenol
- Synonyms
- Bromo-3-fluorophenol;3-Fluoro-2-bromophenol;2-BROMO-3-FLUOROPHENOL;Phenol, 2-bromo-3-fluoro-;2-Bromo-3-fluorophenol ISO 9001：2015 REACH
- CBNumber:
- CB0378327
- Molecular Formula:
- C6H4BrFO
- Molecular Weight:
- 191
- MDL Number:
- MFCD04037220
- MOL File:
- 443-81-2.mol
- MSDS File:
- SDS
| Boiling point | 123 °C(Press: 50 Torr) |
|---|---|
| Density | 1.764±0.06 g/cm3(Predicted) |
| refractive index | 1.56 |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 7.43±0.10(Predicted) |
| form | clear liquid |
| color | Colorless to Light yellow to Light orange |
| CAS DataBase Reference | 443-81-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P260-P280-P310 | |||||||||
| Hazard Codes | T,Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38-22 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| HS Code | 2908190090 | |||||||||
| NFPA 704 |
|
2-Bromo-3-fluorophenol price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B5224 | 2-Bromo-3-fluorophenol >98.0%(GC) | 443-81-2 | 1g | $44 | 2025-07-31 | Buy |
| TCI Chemical | B5224 | 2-Bromo-3-fluorophenol >98.0%(GC) | 443-81-2 | 5g | $175 | 2025-07-31 | Buy |
| TRC | B685170 | 2-Bromo-3-fluorophenol | 443-81-2 | 10g | $385 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB33796 | 2-Bromo-3-fluorophenol | 443-81-2 | 10g | $150 | 2021-12-16 | Buy |
| Matrix Scientific | 072862 | 2-Bromo-3-fluorophenol 95+% | 443-81-2 | 100g | $650 | 2021-12-16 | Buy |
2-Bromo-3-fluorophenol Chemical Properties,Uses,Production
Description
2-Bromo-3-fluorophenol is a chemical intermediate commonly used in organic synthesis and laboratory research. It can be used to prepare monofluorophenol.
Chemical Properties
light yellow liquid
Uses
2-Bromo-3-fluorophenol has been used as a reactant in the preparation of diaryl ethers.
Synthesis
324769-11-1
443-81-2
1. 120 mL of isopropanol, 200 mL of 6M hydrochloric acid and 81 g (345 mmol) of 1-(methoxymethoxy)-2-bromo-3-fluorophenol were mixed and stirred for 2.5 hours at room temperature. 2. Upon completion of the reaction, the reaction mixture was partitioned. 400 ml of methyl tert-butyl ether and 120 ml of 5N sodium hydroxide were added. 3. The organic phase was separated, washed with saturated aqueous sodium chloride solution and then dried over anhydrous sodium sulfate. 4. The dried organic phase is concentrated under pressure to give an oily residue. 5. purify the residue by silica gel column chromatography and collect the fraction containing 2-bromo-3-fluorophenol. 6. Concentrate the combined fractions under pressure to give 55.1 g (84% yield) of the target compound 2-bromo-3-fluorophenol as a colorless oil.
References
[1] Patent: EP1204660, 2004, B1. Location in patent: Page 19
2-Bromo-3-fluorophenol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29733 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49730 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29804 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10035 | 58 |
| Shanghai Safer Pharmaceutical Technology Co., Ltd. | 021-31761238 | sales@saferph.com | CHINA | 897 | 58 |
View Lastest Price from 2-Bromo-3-fluorophenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-02-22 | 2-Bromo-3-fluorophenol
443-81-2
|
US $0.00 / KG | 1KG | 97.5% | 100 tons | Honest Joy Holdings Limited | |
 |
2021-08-12 | 2-Bromo-3-fluorophenol
443-81-2
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-13 | 2-Bromo-3-fluorophenol
443-81-2
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 2-Bromo-3-fluorophenol
443-81-2
- US $0.00 / KG
- 97.5%
- Honest Joy Holdings Limited
-
- 2-Bromo-3-fluorophenol
443-81-2
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 2-Bromo-3-fluorophenol
443-81-2
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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