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2-Bromo-3-fluoroanisole

CAS No.
446-59-3
Chemical Name:
2-Bromo-3-fluoroanisole
Synonyms
Bromo-3-fluoro anisole;2-Bromo-3-fluroanisole;2-BROMO-3-FLUOROANISOLE;2-Bromo-3-fluoroanisole99%;2-Bromo-3-fluoroanisole 99%;REF DUPL: 2-bromo-3-fluoroanisole;2-Bromo-1-fluoro-3-methoxy-benzene;BENZENE,2-BROMO-1-FLUORO-3-METHOXY;2-Bromo-3-fluoroanisole ISO 9001:2015 REACH;2-Bromo-1-fluoro-3-methoxybenzene, 2-Bromo-3-fluorophenyl methyl ether
CBNumber:
CB8485465
Molecular Formula:
C7H6BrFO
Molecular Weight:
205.02
MDL Number:
MFCD03788540
MOL File:
446-59-3.mol
MSDS File:
SDS
Last updated:2026-05-28 05:20:20

2-Bromo-3-fluoroanisole Properties

Boiling point 189.2±20.0 °C(Predicted)
Density 1.531±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form crystals
color Off-white
CAS DataBase Reference 446-59-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xi
HazardClass  IRRITANT
HS Code  2909303890

2-Bromo-3-fluoroanisole price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FB105372 2-bromo-1-fluoro-3-methoxybenzene 446-59-3 50g $900 2026-06-04 Buy
Biosynth FB105372 2-bromo-1-fluoro-3-methoxybenzene 446-59-3 25g $900 2026-06-04 Buy
Biosynth FB105372 2-bromo-1-fluoro-3-methoxybenzene 446-59-3 250g $900 2026-06-04 Buy
Biosynth FB105372 2-bromo-1-fluoro-3-methoxybenzene 446-59-3 10g $900 2026-06-04 Buy
Biosynth FB105372 2-bromo-1-fluoro-3-methoxybenzene 446-59-3 100g $900 2026-06-04 Buy
Product number Packaging Price Buy
FB105372 50g $900 Buy
FB105372 25g $900 Buy
FB105372 250g $900 Buy
FB105372 10g $900 Buy
FB105372 100g $900 Buy

2-Bromo-3-fluoroanisole Chemical Properties, Uses, Production

Uses

2-Bromo-3-fluoroanisole is a phenyl ether compound with fluorine and bromine functional groups on the benzene ring, which can be used as an organic synthesis raw material or intermediate.

Synthesis

2-Bromo-3-fluorophenol

443-81-2

Iodomethane

74-88-4

2-Bromo-3-fluoroanisole

446-59-3

GENERAL METHOD: 2-Bromo-3-fluorophenol (0.1 mol) was dissolved in DMF (100 mL) and K2CO3 (0.1 mol) and iodomethane (0.1 mol) were added sequentially. The reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, water (400 mL) was added to dilute and the mixture was extracted with hexane. The organic phases were combined, washed with water, dried over anhydrous sodium sulfate, filtered through a silica plug and concentrated under reduced pressure to give 2-bromo-3-fluoroanisole.

References

[1] European Journal of Medicinal Chemistry, 2015, vol. 89, p. 524 - 539

443-81-2
74-88-4
446-59-3
Synthesis of 2-Bromo-3-fluoroanisole from 2-Bromo-3-fluorophenol and Iodomethane
Global Suppliers ( 167)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Shanghai Harvest Chemical Industrial Co., Ltd. 15721252604 17321035817 sales@harvest-chem.com China 2829 64

View Latest Price from 2-Bromo-3-fluoroanisole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Bromo-3-fluoroanisole pictures 2026-09-02 2-Bromo-3-fluoroanisole
446-59-3
$8.00 1KG 99% Henan Fengda Chemical Co., Ltd
2-Bromo-3-fluoroanisole pictures 2022-02-25 2-Bromo-3-fluoroanisole
446-59-3
$10.00 1KG 99% 10Tons Hebei Senko Biotechnology Co., Ltd.
2-Bromo-3-fluoroanisole pictures 2022-01-15 2-Bromo-3-fluoroanisole
446-59-3
1KG 97.9% 100 tons Honest Joy Holdings Limited
BENZENE,2-BROMO-1-FLUORO-3-METHOXY REF DUPL: 2-bromo-3-fluoroanisole Bromo-3-fluoro anisole 2-BROMO-3-FLUOROANISOLE 2-Bromo-1-fluoro-3-methoxy-benzene 2-Bromo-3-fluoroanisole 99% 2-Bromo-3-fluoroanisole99% 2-Bromo-1-fluoro-3-methoxybenzene, 2-Bromo-3-fluorophenyl methyl ether 2-Bromo-3-fluoroanisole ISO 9001:2015 REACH 2-Bromo-3-fluroanisole 446-59-3 Aromatic Halides (substituted)