Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1-(4-Methylphenylsulfonyl)-1,2,4-triazole

1-(4-Methylphenylsulfonyl)-1,2,4-triazole

1-(4-Methylphenylsulfonyl)-1,2,4-triazole Structure
1-(4-Methylphenylsulfonyl)-1,2,4-triazole structure
CAS No.
13578-51-3
Chemical Name:
1-(4-Methylphenylsulfonyl)-1,2,4-triazole
Synonyms
1-Tosyl-1,2,4-triazole;Posaconazole Impurity 153;1-Tosyl-1H-1,2,4-triazole;1-(p-Toluenesulfonyl)-1,2,4-triazole;1-(4-Toluenesulfonyl)-1,2,4-triazole;1-(4-Methylphenylsulfonyl)-1,2,4-triazole;1-(p-Toluenesulfonyl)-1,2,4-triazole;MPST 1-(4-Methylphenylsulfonyl)-1,2,4-triazole;1-(p-Toluenesulfonyl)-1,2,4-triazole≥ 98%(HPLC);1H-1,2,4-Triazole, 1-[(4-methylphenyl)sulfonyl]-
CBNumber:
CB0419794
Molecular Formula:
C9H9N3O2S
Molecular Weight:
223.25
MDL Number:
MFCD00458591
MOL File:
13578-51-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:48:20
Request For Quotation

1-(4-Methylphenylsulfonyl)-1,2,4-triazole Properties

Melting point 106-108℃
Boiling point 417.2±38.0 °C(Predicted)
Density 1.39
storage temp. Sealed in dry,Room Temperature
form powder to crystal
pka -0.84±0.12(Predicted)
color White to Almost white
CAS DataBase Reference 13578-51-3

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
HS Code  2935.90.9500

1-(4-Methylphenylsulfonyl)-1,2,4-triazole price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical T3187 1-(p-Toluenesulfonyl)-1,2,4-triazole >98.0%(HPLC) 13578-51-3 1g $34 2025-07-31 Buy
TCI Chemical T3187 1-(p-Toluenesulfonyl)-1,2,4-triazole >98.0%(HPLC) 13578-51-3 5g $96 2021-12-16 Buy
ChemScene CS-0153033 1-Tosyl-1H-1,2,4-triazole ≥97% 13578-51-3 100g $909 2026-06-04 Buy
ChemScene CS-0153033 1-Tosyl-1H-1,2,4-triazole ≥97% 13578-51-3 500g $30330 2026-06-04 Buy
AK Scientific J53299 1-(4-Toluenesulfonyl)-1,2,4-triazole 95% 13578-51-3 1g $12 2026-06-04 Buy
Product number Packaging Price Buy
T3187 1g $34 Buy
T3187 5g $96 Buy
CS-0153033 100g $909 Buy
CS-0153033 500g $30330 Buy
J53299 1g $12 Buy

1-(4-Methylphenylsulfonyl)-1,2,4-triazole Chemical Properties, Uses, Production

Chemical Properties

White to almost white crystals or powder

Synthesis

1,2,4-Triazole

288-88-0

Tosyl chloride

98-59-9

1-(4-METHYLPHENYLSULFONYL)-1,2,4-TRIAZOLE

13578-51-3

1,2,4-Triazole (9.28 g) was suspended in dichloromethane (110 mL) and dried by adding molecular sieves. Subsequently, triethylamine (13.6 g) was added to the suspension to completely dissolve 1,2,4-triazole. Under stirring, p-toluenesulfonyl chloride (25.62 g) was slowly added, taking about 1 hour. After addition, the reaction mixture was continued to be stirred for 30 minutes and then stirred overnight at room temperature. After completion of the reaction, the precipitated salt was removed by filtration. The filtrate was sequentially washed with water and dried with anhydrous sodium sulfate. After filtration to remove the desiccant, the filtrate was concentrated by rotary evaporator. Cyclohexane (300 mL) was added to the concentrated residue and left overnight to crystallize the product. The white crystals were collected by filtration, washed with cyclohexane (50 mL) and dried in an oven at 50 °C to give 1-(4-methylbenzenesulfonyl)-1,2,4-triazole 25.1 g in 83.7% yield, melting point 105-107 °C.

References

[1] Carbohydrate Research, 2003, vol. 338, # 5, p. 451 - 453
[2] Journal of Organic Chemistry, 2010, vol. 75, # 8, p. 2722 - 2725
[3] Patent: US2008/76933, 2008, A1. Location in patent: Page/Page column 3-5
[4] Patent: EP1258480, 2002, A1. Location in patent: Page 37
[5] Journal of Chemical Research, 2016, vol. 40, # 2, p. 101 - 106

1-(4-Methylphenylsulfonyl)-1,2,4-triazole Preparation Products And Raw materials

Raw materials

1,2,4-Triazole Tosyl chloride Sodium p-toluenesulfinate Triethylamine Dichloromethane

Preparation Products

1-(4-Methylphenylsulfonyl)-1,2,4-triazole Suppliers

Global Suppliers ( 76)
Supplier Tel Email Country ProdList Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Beijing Isomersyn Technology CO;LTD 010-82954736 13391601435 sales@isomersyn.com China 3294 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
ZhengZhou HuaWen Chemical Co.Ltd 0370-2785118 17550508557 675141927@qq.com China 3201 55
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80
Cantotech Chemicals, Ltd. 86-0755-86635001 cantotech@126.com China 4554 55
Supplier Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
TCI (Shanghai) Development Co., Ltd. 81
ShangHai DEMO Chemical Co.,Ltd 57
Adamas Reagent, Ltd. 59
Beijing Isomersyn Technology CO;LTD 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Hunan Hui Bai Shi Biotechnology Co., Ltd. 62
ZhengZhou HuaWen Chemical Co.Ltd 55
TOKYO CHEMICAL INDUSTRY CO., LTD. 80
Cantotech Chemicals, Ltd. 55

View Latest Price from 1-(4-Methylphenylsulfonyl)-1,2,4-triazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-(4-METHYLPHENYLSULFONYL)-1,2,4-TRIAZOLE pictures 2025-04-04 1-(4-METHYLPHENYLSULFONYL)-1,2,4-TRIAZOLE
13578-51-3
 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
1-(4-Methylphenylsulfonyl)-1,2,4-triazole pictures 2022-01-26 1-(4-Methylphenylsulfonyl)-1,2,4-triazole
13578-51-3
 1KG 98.7% 100 tons Honest Joy Holdings Limited
1-(4-METHYLPHENYLSULFONYL)-1,2,4-TRIAZOLE pictures 2021-07-13 1-(4-METHYLPHENYLSULFONYL)-1,2,4-TRIAZOLE
13578-51-3
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

13578-51-3 (1-(4-Methylphenylsulfonyl)-1,2,4-triazole) Related Search:

Tungsten p-Toluenesulfonamide Mesitylene-2-sulfonyl chloride 1-[(4-Methylphenyl)sulfonyl]-1H-imidazole Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
1-(4-Methylphenylsulfonyl)-1,2,4-triazole 1-Mesitylenesulfonyl-1,2,4-triazole 1-(2,4,6-Triisopropylbenzenesulfonyl)-3-nitro-1H-1,2,4-triazole N-(3-(Dimethylamino)-1-[(4-methylphenyl)sulfonyl]-1H-1,2,4-triazol-5-yl)-N,N-dimethylamine 1-[[2,4,6-Tris(isopropyl)phenyl]sulphonyl]-1H-1,2,4-triazole
1-(Mesitylene-2-sulfonyl)-3-nitro-1,2,4-triazole 1-(p-Toluenesulfonyl)-3-nitro-1,2,4-triazole

1of3

1-Tosyl-1H-1,2,4-triazole 1-(p-Toluenesulfonyl)-1,2,4-triazole 1-(p-Toluenesulfonyl)-1,2,4-triazole MPST 1-(4-Methylphenylsulfonyl)-1,2,4-triazole 1-(4-Toluenesulfonyl)-1,2,4-triazole 1-(p-Toluenesulfonyl)-1,2,4-triazole≥ 98%(HPLC) 1-Tosyl-1,2,4-triazole 1H-1,2,4-Triazole, 1-[(4-methylphenyl)sulfonyl]- Posaconazole Impurity 153 1-(4-Methylphenylsulfonyl)-1,2,4-triazole 13578-51-3