2-Hydroxy-5-iodo-benzaldehyde
- CAS No.
- 1761-62-2
- Chemical Name:
- 2-Hydroxy-5-iodo-benzaldehyde
- Synonyms
- AKOS B028970;SALOR-INT L497630-1EA;5-IODOSALICYLALDEHYDE;Iodosalicylaldehyde,5-;5-iodosalicyclaldehyde;LABOTEST-BB LT00137782;5-Iodosalicylaldehyde 97%;5-IODO-2-HYDROXYBENZALDEHYDE;2-Hydroxy-5-iodo-benzaldehyde;Benzaldehyde, 2-hydroxy-5-iodo-
- CBNumber:
- CB0445760
- Molecular Formula:
- C7H5IO2
- Molecular Weight:
- 248.02
- MDL Number:
- MFCD00723501
- MOL File:
- 1761-62-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 98-100 °C (lit.) |
|---|---|
| Boiling point | 282.0±30.0 °C(Predicted) |
| Density | 30 g/mL at 25 °C(lit.) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 7.56±0.18(Predicted) |
| Appearance | Light brown to yellow Solid |
| Sensitive | Light Sensitive |
| InChI | InChI=1S/C7H5IO2/c8-6-1-2-7(10)5(3-6)4-9/h1-4,10H |
| InChIKey | PDFVIWFKGYODKD-UHFFFAOYSA-N |
| SMILES | C(=O)C1=CC(I)=CC=C1O |
| CAS DataBase Reference | 1761-62-2(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 2913000090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
2-Hydroxy-5-iodo-benzaldehyde price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 524328 | 5-Iodosalicylaldehyde 97% | 1761-62-2 | 1g | $85.2 | 2026-04-30 | Buy |
| TCI Chemical | I1175 | 2-Hydroxy-5-iodobenzaldehyde min. 95.0 % | 1761-62-2 | 1G | $30 | 2026-04-30 | Buy |
| TCI Chemical | I1175 | 2-Hydroxy-5-iodobenzaldehyde min. 95.0 % | 1761-62-2 | 5G | $89 | 2026-04-30 | Buy |
| Apolloscientific | OR2966 | 2-Hydroxy-5-iodobenzaldehyde 95% | 1761-62-2 | 250mg | $35 | 2026-06-04 | Buy |
| Apolloscientific | OR2966 | 2-Hydroxy-5-iodobenzaldehyde 95% | 1761-62-2 | 500mg | $45 | 2026-06-04 | Buy |
2-Hydroxy-5-iodo-benzaldehyde Chemical Properties, Uses, Production
Uses
5-Iodosalicylaldehyde may be used to synthesize:
- 5-formylsalicylaldehyde
- 5-ortho-carboranylsalicylaldehyde
- new salen (N,N′-Bis(salicylidene)ethylenediamine) ligands that are tethered to a p-acylthio(phenylacetylene)n linker
General Description
5-Iodosalicylaldehyde is a salicylaldehyde derivative.
Synthesis
90-02-8
1761-62-2
General procedure for the synthesis of 5-iodosalicylaldehyde from salicylaldehyde: To a stirred solution of salicylaldehyde (1 mmol) in dichloromethane (CH2Cl2) or 1,2-dichloroethane ((CH2Cl)2) (0.1 M) was added triphenylphosphorane bis(trifluoromethylsulfonyl)imide (Ph3PAuNTf2) (0.025 mmol, 19 mg; if toluene-ligated Ph3PAuNTf2 complex, the ratio was 2:1), followed by the addition of N-iodosuccinimide (NIS) (1.1 mmol, 248 mg). The reaction mixture was stirred at room temperature or reacted under reflux conditions until complete conversion of salicylaldehyde was confirmed by thin layer chromatography (TLC) monitoring. Upon completion of the reaction, the solvent was evaporated under reduced pressure and the resulting crude product was purified by fast column chromatography using different ratios of hexane and ethyl acetate (EtOAc) as eluents to finally obtain purified 5-iodosalicylaldehyde.
References
[1] Journal of Organic Chemistry, 2015, vol. 80, # 9, p. 4306 - 4312
[2] Synlett, 2014, vol. 25, # 3, p. 399 - 402
[3] European Journal of Organic Chemistry, 2016, vol. 2016, # 12, p. 2177 - 2186
[4] Angewandte Chemie - International Edition, 2007, vol. 46, # 4, p. 572 - 575
[5] Chemistry - A European Journal, 2013, vol. 19, # 7, p. 2442 - 2449
2-Hydroxy-5-iodo-benzaldehyde Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jintan Winbond Chemical Co., Ltd. | 0519-82610098 18605286750 | sales@huabangchemical.com | China | 153 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Hangzhou Dingxin Biotechnology Co., Ltd. | 0571-88194596 15558156576 | sales@disynchem.com | China | 94 | 55 |
| Wuhan Haizheng Industry & Trade Development Co. Ltd | 027-8866 0053/88660577/88660578 | China | 1070 | 55 |
View Latest Price from 2-Hydroxy-5-iodo-benzaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-12 | 2-HYDROXY-5-IODO-BENZALDEHYDE
1761-62-2
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2020-01-13 | 2-HYDROXY-5-IODO-BENZALDEHYDE
1761-62-2
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 2-HYDROXY-5-IODO-BENZALDEHYDE
1761-62-2
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 2-HYDROXY-5-IODO-BENZALDEHYDE
1761-62-2
- $1.00
- 99%
- Career Henan Chemical Co
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